Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 9/20 | 0.44 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838545 | 0.78 | GABRA1 (0.36) | — | |
| SCHEMBL28184235 | 0.75 | GABRA1 (0.41) | — | |
| SCHEMBL19143776 | 0.70 | TYR (0.46) | — | |
| SCHEMBL22170510 | 0.68 | ALDH1A1 (0.31) | — | |
| SCHEMBL2262771 | 0.67 | ALDH1A1 (0.35) | — | |
| SCHEMBL14174900 | 0.67 | KCNH2 (0.58) | — | |
| SCHEMBL28293306 | 0.67 | TYR (0.56) | HTR2AHTR2CSLC6A2 | |
| SCHEMBL28794561 | 0.67 | HTR2A (0.68) | HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL10425559 | 0.66 | HTR2A (0.42) | HTR2AHTR2CHTR2BSLC6A2DRD2 | |
| SCHEMBL598503 | 0.66 | TDP2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020138499-A1 | ALKYL-SUBSTITUTED COMPOUND | 大日本住友製薬株式会社 | 2020-07-02 | — | — | WO | disclosed |