SCHEMBL9838545

SCHEMBL9838545

CCc1ccc(CCc2ccc(CC)c(C)c2C)c(C)c1C

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.36
GABRB2 P47870 3/20 0.36
CTRC Q99895 1/20 0.34
TYR P14679 1/20 0.33
BACE1 P56817 1/20 0.30
METAP2 P50579 1/20 0.30
KCNJ1 P48048 1/20 0.30
KCNH2 Q12809 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28184235 0.91 GABRA1 (0.41) GABRA1GABRB2CTRCTYRMETAP2
SCHEMBL19143776 0.85 TYR (0.46) CTRCTYRMETAP2
SCHEMBL9839875 0.83 GABRA1 (0.50) GABRA1GABRB2KCNH2
SCHEMBL28293306 0.81 TYR (0.56) TYRKCNH2
SCHEMBL2262771 0.81 ALDH1A1 (0.35)
SCHEMBL31095112 0.80 TDP2 (0.37) GABRA1GABRB2CTRC
SCHEMBL598503 0.80 TDP2 (0.37) GABRA1GABRB2CTRC
Water SCHEMBL28055285 0.79 TYR (0.55) TYRKCNH2
SCHEMBL22170679 0.78 HTR2A (0.44)
SCHEMBL9839922 0.77 TAAR1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0290050-B1 METHOD FOR PRODUCING ALKYLSTYRENE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-08-21 EP disclosed
US-5026939-A Cracking 1,2-di(4-isobutylphenyl)ethane in contact with acid catalyst NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-06-25 US disclosed
EP-0290050-A1 Method for producing alkylstyrene NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-11-09 EP disclosed