Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28087713 | 0.94 | L3MBTL1 (0.41) | MAPTATRL3MBTL1IRAK4ROCK2 | |
| SCHEMBL16845708 | 0.85 | L3MBTL1 (0.57) | MAPTL3MBTL1ROCK2ROCK1MEN1 | |
| SCHEMBL16845737 | 0.84 | IRAK4 (0.51) | L3MBTL1IRAK4MEN1KMT2ANPC1 | |
| SCHEMBL16845739 | 0.84 | L3MBTL1 (0.43) | MAPTL3MBTL1IRAK4ROCK2ROCK1 | |
| SCHEMBL16845713 | 0.82 | AXL (0.43) | MAPTL3MBTL1IRAK4ROCK2ROCK1 | |
| SCHEMBL16845710 | 0.82 | ROCK1 (0.47) | MAPTL3MBTL1ROCK2ROCK1MEN1 | |
| SCHEMBL22176838 | 0.81 | L3MBTL1 (0.41) | MAPTL3MBTL1IRAK4ROCK2ROCK1 | |
| SCHEMBL16845644 | 0.79 | TRPA1 (0.44) | MAPTL3MBTL1IRAK4ROCK2ROCK1 | |
| SCHEMBL16845744 | 0.79 | MKNK1 (0.52) | L3MBTL1IRAK4ROCK2ROCK1MKNK1 | |
| SCHEMBL24651346 | 0.77 | MAPT (0.39) | MAPTL3MBTL1TSHRIRAK4ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220204473-A1 | COMPOUND AS IRAK INHIBITOR | WUHAN CREATERNA SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2022-06-30 | — | — | US | disclosed |
| EP-3889150-A1 | COMPOUND SERVING AS IRAK INHIBITOR | Shanghai Meiyue Biotech Development Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020135513-A1 | COMPOUND SERVING AS IRAK INHIBITOR | 上海美悦生物科技发展有限公司 | 2020-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220204473-A1 | COMPOUND AS IRAK INHIBITOR | IRAK1, IRAK3, IRAK2 | MAPT 1003/4885ATR 217/4885L3MBTL1 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.