Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22176843 | 0.94 | MAPT (0.43) | L3MBTL1ROCK2ROCK1MAPTMEN1 | |
| SCHEMBL16845708 | 0.86 | L3MBTL1 (0.57) | L3MBTL1ROCK2ROCK1MAPTMEN1 | |
| SCHEMBL16845739 | 0.85 | L3MBTL1 (0.43) | L3MBTL1ROCK2ROCK1MAPTMEN1 | |
| SCHEMBL16845713 | 0.84 | AXL (0.43) | L3MBTL1ROCK2ROCK1MAPTMEN1 | |
| SCHEMBL16845710 | 0.84 | ROCK1 (0.47) | L3MBTL1ROCK2ROCK1MAPTMEN1 | |
| SCHEMBL16845737 | 0.82 | IRAK4 (0.51) | L3MBTL1MEN1KMT2AIRAK4NPC1 | |
| SCHEMBL22176838 | 0.82 | L3MBTL1 (0.41) | L3MBTL1ROCK2ROCK1MAPTMEN1 | |
| SCHEMBL16845644 | 0.80 | TRPA1 (0.44) | L3MBTL1ROCK2ROCK1MAPTMEN1 | |
| SCHEMBL16845744 | 0.80 | MKNK1 (0.52) | L3MBTL1ROCK2ROCK1IRAK4 | |
| SCHEMBL27228043 | 0.77 | TRPA1 (0.41) | L3MBTL1ROCK2ROCK1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106170486-A | Novel indazolecarboxamides, method for the production thereof, pharmaceutical preparations containing the same and use thereof for producing medicaments | 拜耳医药股份有限公司 | 2016-11-30 | — | — | CN | disclosed |