Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23022589 | 0.91 | MAPT (0.36) | MAPTL3MBTL1IRAK4TSHRROCK2 | |
| SCHEMBL19687762 | 0.89 | MAPT (0.36) | MAPTL3MBTL1IRAK4TSHRROCK2 | |
| SCHEMBL21863731 | 0.83 | DHODH (0.38) | MAPTL3MBTL1IRAK4TSHRROCK2 | |
| SCHEMBL21216701 | 0.82 | MAPT (0.36) | MAPTL3MBTL1IRAK4TSHRROCK2 | |
| SCHEMBL22176843 | 0.77 | MAPT (0.43) | MAPTL3MBTL1IRAK4TSHRROCK2 | |
| SCHEMBL20883618 | 0.72 | L3MBTL1 (0.34) | MAPTL3MBTL1ROCK2ROCK1MEN1 | |
| SCHEMBL18183739 | 0.71 | TSHR (0.49) | MAPTL3MBTL1TSHRROCK2ROCK1 | |
| SCHEMBL28087713 | 0.71 | L3MBTL1 (0.41) | MAPTL3MBTL1IRAK4ROCK2ROCK1 | |
| SCHEMBL16845679 | 0.70 | IRAK4 (0.49) | MAPTL3MBTL1IRAK4TSHRMEN1 | |
| SCHEMBL20909097 | 0.70 | L3MBTL1 (0.35) | MAPTL3MBTL1ROCK2ROCK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174508-A1 | SUBSTITUTED INDAZOLES, METHODS FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS THAT CONTAIN SAID NEW SUBSTITUTED INDAZOLES, AND USE OF SAID NEW SUBSTITUTED INDAZOLES TO PRODUCE DRUGS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2023-06-08 | — | — | US | disclosed |
| US-20220249456-A1 | USE OF 2-SUBSTITUTED INDAZOLES FOR THE TREATMENT AND PROPHYLAXIS OF AUTOIMMUNE DISEASES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174508-A1 | SUBSTITUTED INDAZOLES, METHODS FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS THAT CONTAIN SAID NEW SUBSTITUTED INDAZOLES, AND USE OF SAID NEW SUBSTITUTED INDAZOLES TO PRODUCE DRUGS | CYP11B2, CYP11B1, CYP19A1 | MAPT 1069/4885L3MBTL1 4434/4885IRAK4 230/4885 |
| US-20220249456-A1 | USE OF 2-SUBSTITUTED INDAZOLES FOR THE TREATMENT AND PROPHYLAXIS OF AUTOIMMUNE DISEASES | IDO2, IL33, IDO1 | MAPT 1611/4885L3MBTL1 4357/4885IRAK4 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.