SCHEMBL221780

SCHEMBL221780

CC(C)(C)CCS(N)(=O)=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 1/20 0.33
CA2 P00918 3/20 0.32
CA1 P00915 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7205373 0.97 ARG1 (0.32) ARG1CA2CA1
SCHEMBL7204059 0.83 CA2 (0.33) ARG1CA2
SCHEMBL13668109 0.81 CA2 (0.37) ARG1CA2
SCHEMBL29596201 0.78 CA2 (0.52) ARG1CA2
SCHEMBL12141473 0.75 APEX1 (0.30)
SCHEMBL8315548 0.74 ARG1 (0.33) ARG1CA2
SCHEMBL3089492 0.73
SCHEMBL2625547 0.73 NLRP3 (0.38)
SCHEMBL8556536 0.72
SCHEMBL8555178 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230094952-A1 Method for Culturing Hematopoietic Stem Cells Sumitomo Pharma Co., Ltd. (JP) 2023-03-30 US disclosed
EP-4071239-A1 METHOD FOR CULTURING HEMATOPOIETIC STEM CELLS Sumitomo Pharma Co., Ltd. (JP) 2022-10-12 EP disclosed
US-20220017505-A1 AMINOQUINAZOLINONE AND AMINOISOQUINOLINONE DERIVATIVES AND APPLICATION THEREOF SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2022-01-20 US disclosed
US-11052155-B2 Conjugates of CC-1065 analogs and bifunctional linkers SYNTARGA BV (NL) 2021-07-06 US disclosed
WO-2021132627-A1 METHOD FOR CULTURING HEMATOPOIETIC STEM CELLS 大日本住友製薬株式会社 2021-07-01 WO disclosed
EP-3191471-B1 4,5-DIHYDROPYRAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY ABBVIE DEUTSCHLAND (DE) 2020-03-11 EP disclosed
US-10458995-B2 Combinatorial synthesis and biomarker development TEN30 BIOSCIENCES, INC. 2019-10-29 US disclosed
US-20190113521-A1 COMBINATORIAL SYNTHESIS AND BIOMARKER DEVELOPMENT TEN30 BIOSCIENCES, INC. 2019-04-18 US disclosed
US-20180147289-A9 Novel Conjugates of CC-1065 Analogs and Bifunctional Linkers SYNTARGA BV (NL) 2018-05-31 US disclosed
US-20180147289-A9 Novel Conjugates of CC-1065 Analogs and Bifunctional Linkers SYNTARGA BV (NL) 2018-05-31 US disclosed
US-6124494-A Anti-viral compounds ELI LILLY AND COMPANY (US) 2000-09-26 US disclosed
US-6103922-A Anti-viral compounds ELI LILLY AND COMPANY (US) 2000-08-15 US disclosed
US-6103923-A Anti-viral compounds ELI LILLY AND COMPANY (US) 2000-08-15 US disclosed
US-6100426-A Anti-viral compounds ELI LILLY AND COMPANY (US) 2000-08-08 US disclosed
EP-0811600-A2 Anti-viral compounds ELI LILLY AND COMPANY (US) 1997-12-10 EP disclosed
EP-0811599-A2 Anti-viral compounds ELI LILLY AND COMPANY (US) 1997-12-10 EP disclosed
EP-0806203-A2 Anti-viral compositions ELI LILLY AND COMPANY (US) 1997-11-12 EP disclosed
EP-0806409-A1 Anti-viral compounds ELI LILLY AND COMPANY (US) 1997-11-12 EP disclosed
EP-0806410-A2 Anti-viral compounds ELI LILLY AND COMPANY (US) 1997-11-12 EP disclosed
EP-0806408-A1 Anti-viral compounds ELI LILLY AND COMPANY (US) 1997-11-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230094952-A1 Method for Culturing Hematopoietic Stem Cells HCLS1, KIT, MCL1 ARG1 371/4885CA2 1709/4885CA1 864/4885
US-20220017505-A1 AMINOQUINAZOLINONE AND AMINOISOQUINOLINONE DERIVATIVES AND APPLICATION THEREOF PIK3R5, PIK3CA, PIK3R1 ARG1 1860/4885CA2 3404/4885CA1 4619/4885
US-20190113521-A1 COMBINATORIAL SYNTHESIS AND BIOMARKER DEVELOPMENT APP, PSEN2, PSEN1 ARG1 593/4885CA2 1773/4885CA1 43/4885
US-11052155-B2 Conjugates of CC-1065 analogs and bifunctional linkers PCNA, DCLRE1A, CDC5L ARG1 2845/4885CA2 564/4885CA1 439/4885
US-20180147289-A9 Novel Conjugates of CC-1065 Analogs and Bifunctional Linkers PCNA, DCLRE1A, CDC5L ARG1 3078/4885CA2 721/4885CA1 447/4885
US-10458995-B2 Combinatorial synthesis and biomarker development APP, PSEN2, PSEN1 ARG1 520/4885CA2 1712/4885CA1 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.