Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221780 | 0.97 | ARG1 (0.33) | ARG1CA2CA1 | |
| SCHEMBL7204059 | 0.81 | CA2 (0.33) | ARG1CA2 | |
| SCHEMBL13668109 | 0.79 | CA2 (0.37) | ARG1CA2 | |
| SCHEMBL29596201 | 0.76 | CA2 (0.52) | ARG1CA2 | |
| SCHEMBL12141473 | 0.73 | APEX1 (0.30) | — | |
| SCHEMBL8315548 | 0.72 | ARG1 (0.33) | ARG1CA2 | |
| SCHEMBL2625547 | 0.71 | NLRP3 (0.38) | — | |
| SCHEMBL3089492 | 0.71 | — | — | |
| SCHEMBL8555178 | 0.70 | — | — | |
| SCHEMBL8556536 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610518-B2 | Using Cytochrome p450 | PFIZER INC. | 2003-08-26 | — | — | US | disclosed |
| US-20020012977-A1 | Enzymatic oxidations | PFIZER PRODUCTS INC. | 2002-01-31 | — | — | US | disclosed |
| EP-1160331-A1 | Enzymatic oxidations | Pfizer Limited (GB) | 2001-12-05 | — | — | EP | disclosed |