Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23912318 | 0.85 | ALDH1A1 (0.43) | MAPTEPHX2MAPK10ELANEPARP10 | |
| SCHEMBL24213545 | 0.82 | HDAC1 (0.42) | MAPTMAPK10ELANERAB9ACYP17A1 | |
| SCHEMBL24213565 | 0.73 | ROCK1 (0.39) | CYP17A1CYP1A2CYP3A4PRMT1 | |
| SCHEMBL7878972 | 0.72 | EPHX2 (0.41) | EPHX2MAPK10ESRRGRAB9ACYP17A1 | |
| SCHEMBL24290033 | 0.72 | MAPK1 (0.40) | MAPTMAPK10RAB9ALMNANPC1 | |
| SCHEMBL14896662 | 0.72 | MASP2 (0.39) | MAPTPARP10RAB9ALMNACYP1A2 | |
| SCHEMBL7438712 | 0.72 | ADRB2 (0.40) | MAPTEPHX2ELANEADRB2ADRB1 | |
| SCHEMBL14896712 | 0.71 | ADRB2 (0.36) | MAPTEPHX2ESRRGPARP10RAB9A | |
| SCHEMBL15588634 | 0.71 | MEN1 (0.46) | MAPTEPHX2PTGS1ESRRGRAB9A | |
| SCHEMBL24290006 | 0.71 | P2RX7 (0.40) | MAPK10RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134688-A1 | SALT OF ROCK INHIBITOR, CRYSTAL FORM OF SALT, COMPOSITION, AND PHARMACEUTICAL USE | 武汉朗来科技发展有限公司 | 2023-07-20 | — | — | WO | disclosed |
| WO-2022012409-A1 | ROCK INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉朗来科技发展有限公司 | 2022-01-20 | — | — | WO | disclosed |
| WO-2020140052-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. (US) | 2020-07-02 | — | — | WO | disclosed |