Malonic Acid

Malonic Acid

SCHEMBL2218005

O=C([O-])CC(=O)[O-].O=C([O-])CC(=O)[O-].[Cu+2].[Zn+2]

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA4 P22748 4/20 0.83
CASP1 P29466 1/20 0.41
FFAR3 O14843 2/20 0.37
HDAC3 O15379 2/20 0.37
HDAC1 Q13547 2/20 0.37
HDAC2 Q92769 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
LMNA P02545 2/20 0.35
CA1 P00915 3/20 0.33
CA2 P00918 2/20 0.33
BBOX1 O75936 1/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
FAHD1 Q6P587 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL333873 0.96
Malonic Acid SCHEMBL431221 0.96
Malonic Acid SCHEMBL957647 0.92 CA4 (0.83) CA4CASP1FFAR3HDAC3HDAC1
Malonic Acid SCHEMBL22466326 0.92
Malonic Acid SCHEMBL4365583 0.92 CA4 (0.83) CA4CASP1FFAR3HDAC3HDAC1
Malonic Acid SCHEMBL954992 0.92 CA4 (0.83) CA4CASP1FFAR3HDAC3HDAC1
Malonic Acid SCHEMBL955599 0.92 CA4 (0.83) CA4CASP1FFAR3HDAC3HDAC1
Malonic Acid SCHEMBL19714757 0.87 CA4 (0.91) CA4CASP1FFAR3HDAC3HDAC1
Malonic Acid SCHEMBL2475920 0.87 CA4 (0.91) CA4CASP1FFAR3HDAC3HDAC1
Malonic Acid SCHEMBL3190631 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1993569-B1 ANTI-AGING TREATMENT USING COPPER AND ZINC COMPOSITIONS OMP INC (US) 2014-07-23 EP claimed
EP-4262528-B1 DEVICE AND METHOD FOR CONTINUOUS EVEN APPLICATION OF COMPOSITION TO SKIN KENVUE BRANDS LLC (US) 2026-02-18 EP disclosed
US-12472336-B2 System and method for selective application of cosmetic composition to impart undereye brightening KENVUE BRANDS LLC (US) 2025-11-18 US disclosed
US-12358008-B2 Device for supplying a composition to a pressurized deposition system KENVUE BRANDS LLC (US) 2025-07-15 US disclosed
CN-114206426-B Device and method for applying a cosmetic composition by means of a grated end effector 强生消费者公司 2025-05-09 CN disclosed
US-12178978-B2 Device and method for application of cosmetic compositions through a grated end effector JOHNSON & JOHNSON CONSUMER INC. (US) 2024-12-31 US disclosed
CN-113226158-B Apparatus and method for selectively applying topical compositions using dynamic thresholds 强生消费者公司 2024-10-18 CN disclosed
US-20240335645-A1 SYSTEM AND METHOD FOR SELECTIVE APPLICATION OF COSMETIC COMPOSITION TO IMPART UNDEREYE BRIGHTENING JOHNSON & JOHNSON CONSUMER INC. (US) 2024-10-10 US disclosed
EP-4013294-B1 DEVICE AND METHOD FOR APPLICATION OF COSMETIC COMPOSITIONS THROUGH A GRATED END EFFECTOR JOHNSON & JOHNSON CONSUMER INC (US) 2024-08-14 EP disclosed
EP-3917680-B1 DEVICE FOR SUPPLYING A COMPOSITION TO A PRESSURIZED DEPOSITION SYSTEM JOHNSON & JOHNSON CONSUMER INC (US) 2024-08-14 EP disclosed
US-20220032025-A1 SYSTEM AND METHOD FOR SELECTIVE APPLICATION OF COSMETIC COMPOSITION TO IMPART UNDEREYE BRIGHTENING KENVUE BRANDS LLC 2022-02-03 US disclosed
CN-111615385-A Compositions and methods for treating emphysema and other forms of COPD 肺气肿解决方案私人有限公司 2020-09-01 CN disclosed
EP-1816116-B3 Chemical compositions and methods of making them OMP INC (US) 2016-08-03 EP disclosed
US-8952057-B2 Compositions for anorectal use and methods for treating anorectal disorders JR CHEM, LLC (US) 2015-02-10 US disclosed
EP-1816116-B1 Chemical compositions and methods of making them JR CHEMICALS (US) 2013-11-27 EP disclosed
US-20120177583-A1 COMPOSITIONS FOR ANORECTAL USE AND METHODS FOR TREATING ANORECTAL DISORDERS JR CHEM, LLC 2012-07-12 US disclosed
US-20110178318-A1 METHODS OF MAKING BIMETAL COMPLEXES RAMIREZ JOSE E 2011-07-21 US disclosed
US-7897800-B2 Chemical compositions and methods of making them JR CHEM, LLC (US) 2011-03-01 US disclosed
US-20070203354-A1 Chemical Compositions and Methods of Making Them LSSF II OFFSHORE INVESTMENTS, LP, AS ADMINISTRATIVE AGENT (CA) 2007-08-30 US disclosed
EP-1816116-A1 Chemical compositions and methods of making them JR Chemicals (US) 2007-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203354-A1 Chemical Compositions and Methods of Making Them PARG, PCBP1, POLI CA4 22/4885CASP1 3327/4885FFAR3 4783/4885
US-20120177583-A1 COMPOSITIONS FOR ANORECTAL USE AND METHODS FOR TREATING ANORECTAL DISORDERS APC, ALPI, SLC10A2 CA4 88/4885CASP1 4596/4885FFAR3 2689/4885
US-20110178318-A1 METHODS OF MAKING BIMETAL COMPLEXES SOD1, PARG, PMS2 CA4 198/4885CASP1 3961/4885FFAR3 4872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.