SCHEMBL22180584

SCHEMBL22180584

[N-]=[N+]=NCCNC(=O)CNC[C@H](N)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ OTC P00480 1/20 0.36
▸ GFPT1 Q06210 1/20 0.31
▸ CA2 P00918 1/20 0.31
▸ CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15473014 0.81 OTC (0.40) OTCCA2CA9
SCHEMBL23662885 0.81 CA2 (0.35) CA2CA9
SCHEMBL15469217 0.80 CASR (0.37) OTCGFPT1
SCHEMBL24610028 0.79 OTC (0.44) OTC
SCHEMBL15469244 0.79 OTC (0.44) OTC
SCHEMBL16447237 0.74 NOD1 (0.49) OTC
SCHEMBL14285708 0.74 CA2 (0.36) CA2CA9
SCHEMBL15469218 0.73 GFPT1 (0.36) OTCGFPT1
SCHEMBL20834979 0.73 OTC (0.44) OTCCA2CA9
SCHEMBL16447372 0.72 GFPT1 (0.34) GFPT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200207859-A1 METHODS OF USING ANTI-CD74 ANTIBODIES AND ANTIBODY CONJUGATES IN TREATMENT OF T-CELL LYMPHOMA SUTRO BIOPHARMA, INC. 2020-07-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200207859-A1 METHODS OF USING ANTI-CD74 ANTIBODIES AND ANTIBODY CONJUGATES IN TREATMENT OF T-CELL LYMPHOMA CD74, CD99, CD2 OTC 3953/4885GFPT1 4446/4885CA2 2816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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