SCHEMBL15469217

SCHEMBL15469217

[N-]=[N+]=NCCNC(=O)NC[C@H](N)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CASR P41180 14/20 0.37
▸ GFPT1 Q06210 1/20 0.36
▸ OTC P00480 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16446596 0.83 OTC (0.46) OTC
SCHEMBL20178595 0.83 OTC (0.46) OTC
SCHEMBL16446954 0.81 NOS2 (0.44) —
SCHEMBL16446881 0.81 NOS3 (0.44) —
SCHEMBL17852276 0.81 NOS2 (0.44) —
SCHEMBL28260909 0.81 NOS2 (0.44) —
SCHEMBL22180584 0.80 OTC (0.36) GFPT1OTC
SCHEMBL15473014 0.79 OTC (0.40) OTC
SCHEMBL24610028 0.76 OTC (0.44) OTC
SCHEMBL15469218 0.76 GFPT1 (0.36) GFPT1OTC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026008-A1 ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES SUTRO BIOPHARMA INC (US) 2024-01-25 — — US disclosed
US-20240026008-A1 ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES SUTRO BIOPHARMA INC (US) 2024-01-25 — — US disclosed
US-11744876-B2 Immunomodulator antibody drug conjugates and uses thereof SUTRO BIOPHARMA, INC. (US) 2023-09-05 — — US disclosed
US-11744876-B2 Immunomodulator antibody drug conjugates and uses thereof SUTRO BIOPHARMA, INC. (US) 2023-09-05 — — US disclosed
US-11708413-B2 Anti-CD74 antibody conjugates, compositions comprising anti-CD74 antibody conjugates and methods of using anti-CD74 antibody conjugates SUTRO BIOPHARMA, INC. (US) 2023-07-25 — — US disclosed
US-11708413-B2 Anti-CD74 antibody conjugates, compositions comprising anti-CD74 antibody conjugates and methods of using anti-CD74 antibody conjugates SUTRO BIOPHARMA, INC. (US) 2023-07-25 — — US disclosed
US-20230139442-A1 MODIFIED AMINO ACIDS SUTRO BIOPHARMA, INC. 2023-05-04 — — US disclosed
US-20230139442-A1 MODIFIED AMINO ACIDS SUTRO BIOPHARMA, INC. 2023-05-04 — — US disclosed
US-11548852-B2 Modified amino acids SUTRO BIOPHARMA, INC. (US) 2023-01-10 — — US disclosed
EP-4074728-A1 MODIFIED PEPTIDES COMPRISING AN AZIDO GROUP Sutro Biopharma, Inc. (US) 2022-10-19 — — EP disclosed
US-20160251336-A1 MODIFIED AMINO ACIDS COMPRISING TETRAZINE FUNCTIONAL GROUPS, METHODS OF PREPARATION, AND METHODS OF THEIR USE SUTRO BIOPHARMA, INC. (US) 2016-09-01 — — US disclosed
WO-2015054658-A1 MODIFIED AMINO ACIDS COMPRISING TETRAZINE FUNCTIONAL GROUPS, METHODS OF PREPARATION, AND METHODS OF THEIR USE SUTRO BIOPHARMA, INC. (US) 2015-04-16 — — WO disclosed
WO-2015006555-A2 ANTIBODIES COMPRISING MULTIPLE SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE SUTRO BIOPHARMA, INC. (US) 2015-01-15 — — WO disclosed
US-20140066598-A1 Modified Amino Acids SUTRO BIOPHARMA, INC. (US) 2014-03-06 — — US disclosed
WO-2014036492-A1 MODIFIED AMINO ACIDS COMPRISING AN AZIDO GROUP SUTRO BIOPHARMA, INC. (US) 2014-03-06 — — WO disclosed
US-20140066598-A1 Modified Amino Acids SUTRO BIOPHARMA, INC. (US) 2014-03-06 — — US disclosed
US-20140051836-A1 Modified Fc Proteins Comprising Site-Specific Non-Natural Amino Acid Residues, Conjugates of the Same, Methods of Their Preparation and Methods of Their Use SUTRO BIOPHARMA, INC. 2014-02-20 — — US disclosed
US-20140051836-A1 Modified Fc Proteins Comprising Site-Specific Non-Natural Amino Acid Residues, Conjugates of the Same, Methods of Their Preparation and Methods of Their Use SUTRO BIOPHARMA, INC. 2014-02-20 — — US disclosed
US-20140046030-A1 ANTIBODIES COMPRISING SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE SUTRO BIOPHARMA, INC. (US) 2014-02-13 — — US disclosed
US-20140046030-A1 ANTIBODIES COMPRISING SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE SUTRO BIOPHARMA, INC. (US) 2014-02-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140051836-A1 Modified Fc Proteins Comprising Site-Specific Non-Natural Amino Acid Residues, Conjugates of the Same, Methods of Their Preparation and Methods of Their Use FCGR2A, FCGR3B, FCGR1A CASR 4059/4885GFPT1 373/4885OTC 3494/4885
US-11548852-B2 Modified amino acids PTMS, DNPEP, ANPEP CASR 3959/4885GFPT1 401/4885OTC 1469/4885
US-20240026008-A1 ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES CD74, CD63, CD99 CASR 3449/4885GFPT1 4316/4885OTC 3340/4885
US-11708413-B2 Anti-CD74 antibody conjugates, compositions comprising anti-CD74 antibody conjugates and methods of using anti-CD74 antibody conjugates CD74, CD63, CD99 CASR 3584/4885GFPT1 4241/4885OTC 3319/4885
US-20140066598-A1 Modified Amino Acids PTMS, DNPEP, ANPEP CASR 3959/4885GFPT1 401/4885OTC 1469/4885
US-11744876-B2 Immunomodulator antibody drug conjugates and uses thereof FCGR1A, FCGR2A, FCGRT CASR 3747/4885GFPT1 3002/4885OTC 4749/4885
US-20230139442-A1 MODIFIED AMINO ACIDS PTMS, DNPEP, ANPEP CASR 3959/4885GFPT1 401/4885OTC 1469/4885
US-20160251336-A1 MODIFIED AMINO ACIDS COMPRISING TETRAZINE FUNCTIONAL GROUPS, METHODS OF PREPARATION, AND METHODS OF THEIR USE DNPEP, SLC1A5, AADAT CASR 4086/4885GFPT1 359/4885OTC 1207/4885
US-20140046030-A1 ANTIBODIES COMPRISING SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE DNPEP, LNPEP, ANPEP CASR 3411/4885GFPT1 559/4885OTC 4094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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