Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ACLY | P53396 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29769728 | 0.87 | KDM4E (0.38) | DHPSACLYKDM4EALDH1A1HSD17B10 | |
| SCHEMBL679753 | 0.87 | KDM4E (0.38) | DHPSACLYKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29443526 | 0.86 | ALDH1A1 (0.41) | DHPSACLYKDM4EALDH1A1HSD17B10 | |
| SCHEMBL678359 | 0.86 | ALDH1A1 (0.41) | DHPSACLYKDM4EALDH1A1HSD17B10 | |
| SCHEMBL21584335 | 0.85 | MAPT (0.40) | MAPTKDM4EALDH1A1POLBADORA2A | |
| SCHEMBL679154 | 0.85 | ALDH1A1 (0.40) | DHPSACLYKDM4EALDH1A1HSD17B10 | |
| Potassium SCHEMBL679156 | 0.85 | ALDH1A1 (0.40) | DHPSACLYKDM4EALDH1A1HSD17B10 | |
| SCHEMBL21614326 | 0.84 | ALDH1A1 (0.40) | DHPSMAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL12364193 | 0.83 | MEP1B (0.36) | DHPSMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28100734 | 0.83 | MAPT (0.36) | DHPSMAPTKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020133403-A1 | SUBSTITUTED PYRIMIDINE ARYL ESTER DERIVATIVE, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND APPLICATION THEREOF | 青岛清原化合物有限公司 | 2020-07-02 | — | — | WO | disclosed |