SCHEMBL29443526

SCHEMBL29443526

COc1c(Cl)ccc(-c2nc(N)c(Cl)c(C(=O)O)n2)c1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HSD17B10 Q99714 1/20 0.41
KMO O15229 2/20 0.37
MEP1B Q16820 1/20 0.36
DHPS P49366 1/20 0.35
TPMT P51580 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ACLY P53396 2/20 0.33
SCN10A Q9Y5Y9 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
TAS1R2 Q8TE23 1/20 0.33
DPP4 P27487 1/20 0.32
PRKAB2 O43741 1/20 0.32
PRKAG1 P54619 1/20 0.32
PRKAA2 P54646 1/20 0.32
PRKAA1 Q13131 1/20 0.32
PRKAG3 Q9UGI9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL678359 1.00 ALDH1A1 (0.41) ALDH1A1KDM4EHSD17B10KMOMEP1B
Potassium SCHEMBL679156 0.99 ALDH1A1 (0.40) ALDH1A1KDM4EHSD17B10KMOMEP1B
SCHEMBL679154 0.99 ALDH1A1 (0.40) ALDH1A1KDM4EHSD17B10KMOMEP1B
SCHEMBL678756 0.92 MEP1B (0.38) ALDH1A1KDM4EHSD17B10KMOMEP1B
SCHEMBL1397100 0.91 ALDH1A1 (0.42) ALDH1A1KDM4EHSD17B10KMOMEP1B
SCHEMBL1224599 0.91 ALDH1A1 (0.44) ALDH1A1KDM4EHSD17B10KMODHPS
SCHEMBL1223251 0.90 ALDH1A1 (0.41) ALDH1A1KDM4EHSD17B10KMOMEP1B
SCHEMBL12364193 0.90 MEP1B (0.36) ALDH1A1KDM4EHSD17B10MEP1BDHPS
SCHEMBL1918698 0.89 KDM4E (0.40) ALDH1A1KDM4EHSD17B10KMOMEP1B
SCHEMBL679753 0.89 KDM4E (0.38) ALDH1A1KDM4EHSD17B10MEP1BDHPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122074074-A Pyridine and pyrimidine derivatives as herbicides 先正达农作物保护股份公司 2026-05-22 CN disclosed
EP-4739679-A1 CRYSTALLINE FORMS OF A HERBICIDE AND THEIR COMPOSITIONS Syngenta Crop Protection AG (CH) 2026-05-13 EP disclosed
EP-4702009-A1 HERBICIDAL DERIVATIVES Syngenta Crop Protection AG (CH) 2026-03-04 EP disclosed
WO-2026041514-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2026-02-26 WO disclosed
EP-4688740-A1 FUSED PYRROLIDINE-2-ONE HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2026-02-11 EP disclosed
EP-4649075-A1 HERBICIDAL IMIDAZOLE COMPOUNDS Syngenta Crop Protection AG (CH) 2025-11-19 EP disclosed
EP-4649076-A1 HERBICIDAL PYRAZOLE COMPOUNDS Syngenta Crop Protection AG (CH) 2025-11-19 EP disclosed
EP-4637356-A1 HERBICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2025-10-29 EP disclosed
EP-4626861-A1 HERBICIDAL DERIVATIVES Syngenta Crop Protection AG (CH) 2025-10-08 EP disclosed
EP-4598913-A1 HERBICIDAL IMIDAZOLE COMPOUNDS Syngenta Crop Protection AG (CH) 2025-08-13 EP disclosed
WO-2023144004-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-08-03 WO disclosed
EP-4210489-A1 HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2023-07-19 EP disclosed
WO-2023110664-A1 HERBICIDAL PYRIDONE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-06-22 WO disclosed
WO-2023099354-A1 HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-06-08 WO disclosed
WO-2023088921-A1 HERBICIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-05-25 WO disclosed
CN-113271777-B Compositions comprising clopyralid and other herbicides and methods thereof 美国陶氏益农公司 2023-05-23 CN disclosed
WO-2023066783-A1 HERBICIDAL IMIDAZOLE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 WO disclosed
WO-2023066784-A1 SUBSTITUTED BENZAMIDES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 WO disclosed
CN-114478507-A Pyrimidine oxazole compound and application thereof 东莞市东阳光农药研发有限公司 2022-05-13 CN disclosed
WO-2022053422-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-03-17 WO disclosed