Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22182014 | 0.85 | HEXA (0.36) | USP2KMT2AMEN1ATMMAPT | |
| SCHEMBL22181863 | 0.81 | MEN1 (0.58) | USP2KMT2AMEN1ATMMAPT | |
| SCHEMBL22181838 | 0.77 | HDAC3 (0.35) | KMT2AMEN1L3MBTL1POLBHDAC1 | |
| SCHEMBL29632727 | 0.76 | SIRT1 (0.56) | USP2KMT2AMEN1ATMMAPT | |
| SCHEMBL22181921 | 0.76 | SIRT1 (0.56) | USP2KMT2AMEN1ATMMAPT | |
| SCHEMBL22182070 | 0.74 | HEXA (0.36) | MAPTL3MBTL1POLBHEXAHEXB | |
| SCHEMBL22182116 | 0.70 | TP53 (0.44) | KMT2AMEN1MAPTPOLBHEXA | |
| SCHEMBL8243456 | 0.70 | HDAC8 (0.65) | KMT2AMEN1L3MBTL1HTTHDAC1 | |
| SCHEMBL22181920 | 0.68 | SIRT1 (0.61) | USP2KMT2AMEN1ATMMAPT | |
| SCHEMBL16213588 | 0.68 | HEXA (0.58) | KMT2AMEN1L3MBTL1POLBHEXA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020139291-A1 | NAPHTHALIMIDE DERIVATIVES AS ANTI-PARASITIC AGENTS FOR THE TREATMENT OF LEISHMANIASIS AS WELL AS VIRAL, BACTERIAL AND NEOPLASTIC DISEASES | ISTANBUL MEDIPOL UNIVERSITESI (TR) | 2020-07-02 | — | — | WO | disclosed |