Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 6/20 | 0.36 |
| ▸ | HEXB | P07686 | 6/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22182108 | 0.85 | USP2 (0.41) | HEXAHEXBSIRT1HDAC3HDAC4 | |
| SCHEMBL22181988 | 0.82 | SIRT1 (0.53) | HEXAHEXBSIRT1HDAC3HDAC4 | |
| SCHEMBL22182070 | 0.76 | HEXA (0.36) | HEXAHEXBSIRT1L3MBTL1POLB | |
| SCHEMBL22181838 | 0.74 | HDAC3 (0.35) | HEXAHEXBSIRT1HDAC3HDAC4 | |
| SCHEMBL22181861 | 0.72 | SIRT1 (0.53) | HEXAHEXBSIRT1HDAC3HDAC4 | |
| SCHEMBL22182013 | 0.69 | HEXA (0.62) | HEXAHEXBSIRT1HDAC3HDAC4 | |
| SCHEMBL22182116 | 0.69 | TP53 (0.44) | HEXAHEXBSIRT1KMT2AMEN1 | |
| SCHEMBL22182115 | 0.69 | SIRT1 (0.49) | HEXAHEXBSIRT1HDAC3HDAC4 | |
| SCHEMBL8243456 | 0.68 | HDAC8 (0.65) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16213588 | 0.67 | HEXA (0.58) | HEXAHEXBL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020139291-A1 | NAPHTHALIMIDE DERIVATIVES AS ANTI-PARASITIC AGENTS FOR THE TREATMENT OF LEISHMANIASIS AS WELL AS VIRAL, BACTERIAL AND NEOPLASTIC DISEASES | ISTANBUL MEDIPOL UNIVERSITESI (TR) | 2020-07-02 | — | — | WO | disclosed |