Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 11/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22185212 | 0.84 | CNR2 (0.48) | CNR2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL22185210 | 0.83 | PDE3B (0.40) | CNR2TRPV1CA1CA2CA7 | |
| SCHEMBL22199030 | 0.81 | NQO2 (0.43) | CNR2KDM4EALDH1A1GRIN2DGRIN3B | |
| SCHEMBL22185224 | 0.78 | ALDH1A1 (0.44) | CNR2PDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL22184887 | 0.75 | IDH1 (0.45) | TRPV1PDE3BPDE3AGRIN2DGRIN3B | |
| SCHEMBL22184890 | 0.75 | GRIN2D (0.39) | EIF4A3CNR2TRPV1GRIN2DGRIN3B | |
| SCHEMBL22184937 | 0.74 | EIF4A3 (0.40) | EIF4A3TRPV1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5771632 | 0.73 | GRIN2D (0.38) | CNR2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9095259 | 0.72 | PDE3B (0.46) | CNR2TRPV1PDE3BPDE3AKDM4E | |
| SCHEMBL22185875 | 0.71 | GRIN2D (0.52) | PDE3BPDE3AKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200206233-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200206233-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | IDH1, IDH2, IDH3A | EIF4A3 3498/4885CNR2 4018/4885TRPV1 4635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.