Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | TACR3 | P29371 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22145794 | 0.83 | POLB (0.47) | POLBCNR2CNR1MMP8TACR3 | |
| SCHEMBL11161625 | 0.82 | POLB (0.48) | POLBCNR2CNR1MMP8TACR3 | |
| SCHEMBL11154872 | 0.82 | POLB (0.48) | POLBCNR2CNR1MMP8TACR3 | |
| SCHEMBL20077094 | 0.81 | LMNA (0.53) | POLBCNR2CNR1MMP8MAPT | |
| SCHEMBL14236757 | 0.79 | POLB (0.39) | POLBCNR2CNR1MMP8MAPT | |
| SCHEMBL3787306 | 0.79 | ESRRG (0.43) | POLBMMP8MAPTHIF1ACYP2C19 | |
| SCHEMBL11159885 | 0.78 | POLB (0.48) | POLBCNR2CNR1MMP8TACR3 | |
| SCHEMBL13526147 | 0.78 | DRD2 (0.46) | POLBMMP8MAPTKMT2ADRD2 | |
| SCHEMBL20077095 | 0.78 | MAPT (0.52) | POLBCNR2CNR1TACR3MAPT | |
| SCHEMBL3787301 | 0.77 | EPHX2 (0.47) | POLBMAPTKMT2AHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10974232-B2 | Catalyst, method for forming amide bond, and method for producing amide compound | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2021-04-13 | — | — | US | disclosed |
| US-20200206724-A1 | Catalyst, Method for Forming Amide Bond, and Method for Producing Amide Compound | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200206724-A1 | Catalyst, Method for Forming Amide Bond, and Method for Producing Amide Compound | ASNS, NAAA, PYM1 | POLB 1442/4885CNR2 1103/4885CNR1 798/4885 |
| US-10974232-B2 | Catalyst, method for forming amide bond, and method for producing amide compound | ASNS, NAAA, PYM1 | POLB 1442/4885CNR2 1103/4885CNR1 798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.