Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 10/20 | 0.58 |
| ▸ | NPC1 | O15118 | 9/20 | 0.58 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.57 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.57 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.57 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4965466 | 0.85 | HDAC3 (0.71) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7832010 | 0.81 | HDAC3 (0.66) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28465548 | 0.81 | HDAC3 (0.75) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1576968 | 0.81 | PDK1 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11356431 | 0.80 | L3MBTL1 (0.73) | MEN1KMT2ARAB9ANPC1PDK1 | |
| SCHEMBL28014749 | 0.80 | PDK1 (0.63) | MEN1KMT2ARAB9ANPC1PDK1 | |
| SCHEMBL7038396 | 0.79 | RAB9A (0.55) | MEN1KMT2ARAB9ANPC1PDK1 | |
| SCHEMBL7835891 | 0.79 | HDAC3 (0.63) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL31745201 | 0.78 | PDK1 (0.66) | MEN1KMT2ARAB9ANPC1PDK1 | |
| SCHEMBL673402 | 0.77 | HDAC6 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10974232-B2 | Catalyst, method for forming amide bond, and method for producing amide compound | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2021-04-13 | — | — | US | disclosed |
| US-20200206724-A1 | Catalyst, Method for Forming Amide Bond, and Method for Producing Amide Compound | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2020-07-02 | — | — | US | disclosed |
| CN-108440328-A | A kind of amide takes off boc-protected method | 常熟理工学院 | 2018-08-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200206724-A1 | Catalyst, Method for Forming Amide Bond, and Method for Producing Amide Compound | ASNS, NAAA, PYM1 | HDAC3 793/4885HDAC4 154/4885HDAC1 46/4885 |
| US-10974232-B2 | Catalyst, method for forming amide bond, and method for producing amide compound | ASNS, NAAA, PYM1 | HDAC3 793/4885HDAC4 154/4885HDAC1 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.