SCHEMBL2218613

SCHEMBL2218613

Oc1ccccc1/N=N/c1ccccn1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.61
LMNA P02545 3/20 0.61
MAPT P10636 3/20 0.61
HTT P42858 3/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
KMT2A Q03164 2/20 0.61
NPC1 O15118 2/20 0.61
MEN1 O00255 1/20 0.61
KCNH2 Q12809 11/20 0.60
OPRK1 P41145 2/20 0.57
NPSR1 Q6W5P4 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
PKM P14618 1/20 0.57
MAOA P21397 1/20 0.55
MAOB P27338 1/20 0.55
ALDH1A1 P00352 1/20 0.54
POLB P06746 1/20 0.54
HSP90AA1 P07900 1/20 0.54
HPGD P15428 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1933506 1.00 KDM4E (0.61) KDM4ELMNAMAPTHTTSMN1; SMN2
Water SCHEMBL26684690 0.98 KDM4E (0.59) KDM4ELMNAMAPTHTTSMN1; SMN2
SCHEMBL8087866 0.84 KCNH2 (0.50) KDM4ELMNAMAPTHTTSMN1; SMN2
SCHEMBL1128642 0.82 LMNA (0.65) KDM4ELMNAMAPTHTTSMN1; SMN2
SCHEMBL1128638 0.82 LMNA (0.65) KDM4ELMNAMAPTHTTSMN1; SMN2
SCHEMBL29362645 0.82 KCNH2 (0.67) KDM4ELMNAMAPTHTTSMN1; SMN2
SCHEMBL624306 0.82 KCNH2 (0.67) KDM4ELMNAMAPTHTTSMN1; SMN2
SCHEMBL624305 0.82 KCNH2 (0.67) KDM4ELMNAMAPTHTTSMN1; SMN2
SCHEMBL2593076 0.81 KCNH2 (0.65) KDM4ELMNAMAPTHTTSMN1; SMN2
SCHEMBL2593070 0.81 KCNH2 (0.65) KDM4ELMNAMAPTHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240093278-A1 RAPID MOLECULAR DIAGNOSTICS WITH UNIFIED-ONE-POT SAMPLE PROCESSING, NUCLEIC ACID AMPLIFICATION, AND RESULT READOUT DUKE UNIVERSITY 2024-03-21 US claimed
CN-112540075-A Method and kit for detecting acid value of oil 月旭科技(上海)股份有限公司 2021-03-23 CN claimed
US-12536631-B2 System and method for enhancing visualization of colorimetric assay readouts DOMUS DIAGNOSTICS, INC. (US) 2026-01-27 US disclosed
US-20250382666-A1 ASSAY DEVICE FOR ISOTHERMAL AMPLIFICATION AND DETECTION OF NUCLEIC ACIDS DOMUS DIAGNOSTICS, INC. 2025-12-18 US disclosed
US-20250223635-A1 ULTRA-FAST ONE-POT LOOP-MEDIATED ISOTHERMAL AMPLIFICATION AND DETECTION OF DNA AND RNA DOMUS DIAGNOSTICS, INC. 2025-07-10 US disclosed
WO-2024264054-A2 SYSTEM AND METHOD FOR ENHANCING VISUALIZATION OF COLORIMETRIC ASSAY READOUTS DOMUS DIAGNOSTICS, INC. (US) 2024-12-26 WO disclosed
US-20240428386-A1 SYSTEM AND METHOD FOR ENHANCING VISUALIZATION OF COLORIMETRIC ASSAY READOUTS DOMUS DIAGNOSTICS, INC. 2024-12-26 US disclosed
WO-2024064136-A1 RAPID MOLECULAR DIAGNOSTICS WITH UNIFIED-ONE-POT SAMPLE PROCESSING, NUCLEIC ACID AMPLIFICATION, AND RESULT READOUT DOMUS DIAGNOSTICS, INC. (US) 2024-03-28 WO disclosed
US-20240093278-A1 RAPID MOLECULAR DIAGNOSTICS WITH UNIFIED-ONE-POT SAMPLE PROCESSING, NUCLEIC ACID AMPLIFICATION, AND RESULT READOUT DUKE UNIVERSITY 2024-03-21 US disclosed
US-20240026435-A1 LOOP MEDIATED ISOTHERMAL NUCLEIC ACID AMPLIFICATION (LAMP) USING LNA-MODIFIED PRIMERS AND A METAL-BASED COLORIMETRIC METHOD FOR DETECTING AN AMPLIFICATION PRODUCT MultiplexDX, s.r.o. (SK) 2024-01-25 US disclosed
US-20240026435-A1 LOOP MEDIATED ISOTHERMAL NUCLEIC ACID AMPLIFICATION (LAMP) USING LNA-MODIFIED PRIMERS AND A METAL-BASED COLORIMETRIC METHOD FOR DETECTING AN AMPLIFICATION PRODUCT MultiplexDX, s.r.o. (SK) 2024-01-25 US disclosed
CN-112540075-A Method and kit for detecting acid value of oil 月旭科技(上海)股份有限公司 2021-03-23 CN disclosed
US-20110178132-A1 PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2011-07-21 US disclosed
US-5221626-A Adding a 2-pyridylazo-aminophenol deriving zinc coloring reagent and a mixture of a surfactant, salicylaldoxime and dimethyglyoxime which masks nickel, cobalt, iron or cooper to a serum sample and measuring absorbance of solution WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 1993-06-22 US disclosed
EP-0147660-A2 Colorimetric measuring method for zinc WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1985-07-10 EP disclosed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4171221-A NONSILVER PHOTOGTAPHY EASTMAN KODAK COMPANY (US) 1979-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110178132-A1 PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL C5, PRDX1, PRDX4 KDM4E 624/4885LMNA 3940/4885MAPT 4550/4885
US-12536631-B2 System and method for enhancing visualization of colorimetric assay readouts NR2E3, PDE6C, PDE6H KDM4E 4415/4885LMNA 557/4885MAPT 3771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.