Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128642 | 1.00 | LMNA (0.65) | LMNAMAPTALDH1A1KDM4EOPRK1 | |
| SCHEMBL10790402 | 0.98 | LMNA (0.63) | LMNAMAPTALDH1A1KDM4EOPRK1 | |
| SCHEMBL591141 | 0.98 | LMNA (0.63) | LMNAMAPTALDH1A1KDM4EOPRK1 | |
| SCHEMBL591140 | 0.98 | LMNA (0.63) | LMNAMAPTALDH1A1KDM4EOPRK1 | |
| SCHEMBL10790408 | 0.98 | LMNA (0.63) | LMNAMAPTALDH1A1KDM4EOPRK1 | |
| SCHEMBL2470956 | 0.82 | MAOA (0.77) | LMNAMAPTALDH1A1KDM4EOPRK1 | |
| SCHEMBL275526 | 0.82 | MAOA (0.77) | LMNAMAPTALDH1A1KDM4EOPRK1 | |
| SCHEMBL29785641 | 0.82 | MAOA (0.77) | LMNAMAPTALDH1A1KDM4EOPRK1 | |
| SCHEMBL1933506 | 0.82 | KDM4E (0.61) | LMNAMAPTALDH1A1KDM4EOPRK1 | |
| SCHEMBL2218613 | 0.82 | KDM4E (0.61) | LMNAMAPTALDH1A1KDM4EOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020187558-A1 | Method for determining the amount of metal in water and kit therefor | ADVANCED EXPLORATION & RESEARCH, INC. | 2002-12-12 | — | — | US | claimed |
| US-4681828-A | Method of chemical electrographic image amplification using chemically active toner particles | EASTMAN KODAK COMPANY (US) | 1987-07-21 | — | — | US | claimed |
| US-4084967-A | Photographic elements containing vesicles of rhodopsin and lipids | EASTMAN KODAK COMPANY (US) | 1978-04-18 | — | — | US | claimed |
| US-4057427-A | PHOTOGRAPHY | EASTMAN KODAK COMPANY (US) | 1977-11-08 | — | — | US | claimed |
| US-20170209400-A1 | METHODS AND TOPICAL FORMULATIONS FOR TREATING INFLAMMATION | LIVIONEX INC (US) | 2017-07-27 | — | — | US | disclosed |
| US-9616127-B2 | Method and topical formulation for treating localized edema | LIVIONEX INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-9614165-B2 | Photoelectric conversion element, dye-sensitized solar cell, metal complex dye, dye solution, dye-adsorbed electrode and method of producing dye-sensitized solar cell | FUJIFILM CORPORATION (JP) | 2017-04-04 | — | — | US | disclosed |
| EP-2933875-B1 | PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, DYE-ADSORBED ELECTRODE, AND METHOD FOR PRODUCING DYE-SENSITIZED SOLAR CELL | FUJIFILM CORP (JP) | 2017-03-29 | — | — | EP | disclosed |
| EP-2933875-A1 | PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, DYE-ABSORBED ELECTRODE, AND METHOD FOR MANUFACTURING DYE-SENSITIZED SOLAR CELL | Fujifilm Corporation (JP) | 2015-10-21 | — | — | EP | disclosed |
| US-20150280145-A1 | PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, DYE-ABSORBED ELECTRODE AND METHOD OF PRODUCING DYE-SENSITIZED SOLAR CELL | FUJIFILM CORPORATION (JP) | 2015-10-01 | — | — | US | disclosed |
| EP-2282729-A1 | METHODS AND COMPOSITIONS FOR TREATING INFLAMMATION AND INFLAMMATION-RELATED PATHOLOGIES | Livionex Inc. (US) | 2011-02-16 | — | — | EP | disclosed |
| US-20100069335-A1 | Prevention and Treatment of Ophthalmic Complications of Diabetes | LIVIONEX INC. | 2010-03-18 | — | — | US | disclosed |
| EP-1146062-A1 | Method of producing crosslinkable silyl group-containing polyoxyalkylene polymers | Kaneka Corporation (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-6022879-A | TREATING AMYOTROPHIC LATERAL SCLEROSIS; NEOCUPROINE | UAB RESEARCH FOUNDATION (US) | 2000-02-08 | — | — | US | disclosed |
| WO-1999018958-A1 | BATHOCUPROINE TREATMENT OF NEUROLOGIC DISEASE | UAB RESEARCH FOUNDATION (US) | 1999-04-22 | — | — | WO | disclosed |
| EP-0382400-A2 | Immunoassay process and liquid reagents used therefor | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1990-08-16 | — | — | EP | disclosed |
| US-4681828-A | Method of chemical electrographic image amplification using chemically active toner particles | EASTMAN KODAK COMPANY (US) | 1987-07-21 | — | — | US | disclosed |
| US-4131463-A | Electric recording process of images using electron sensitive layer containing trivalent cobalt complex and compound having conjugated π bond system | FUJI PHOTO FILM CO., LTD. (JP) | 1978-12-26 | — | — | US | disclosed |
| US-4084967-A | Photographic elements containing vesicles of rhodopsin and lipids | EASTMAN KODAK COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4057427-A | PHOTOGRAPHY | EASTMAN KODAK COMPANY (US) | 1977-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069335-A1 | Prevention and Treatment of Ophthalmic Complications of Diabetes | SLC5A1, SLC2A8, SMS | LMNA 2101/4885MAPT 4436/4885ALDH1A1 2737/4885 |
| US-20170209400-A1 | METHODS AND TOPICAL FORMULATIONS FOR TREATING INFLAMMATION | MMP8, CXCL8, MMP1 | LMNA 4562/4885MAPT 3632/4885ALDH1A1 4592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.