SCHEMBL22186232

SCHEMBL22186232

c1ccc(-c2ccc(-c3nc(-c4ccc(-c5ccccc5)cc4)nc(-c4ccc5c(ccc6ccccc65)c4)n3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
LMNA P02545 2/20 0.50
NPC1 O15118 1/20 0.50
RECQL P46063 1/20 0.50
RAB9A P51151 1/20 0.50
ALDH1A1 P00352 7/20 0.48
HSD17B10 Q99714 4/20 0.48
CYP1B1 Q16678 2/20 0.48
HIF1A Q16665 1/20 0.48
HPRT1 P00492 2/20 0.46
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
HPGD P15428 4/20 0.46
CYP1A2 P05177 3/20 0.45
KDM4E B2RXH2 3/20 0.45
TP53 P04637 2/20 0.45
TSHR P16473 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
CYP2A6 P11509 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21667500 1.00 MAPT (0.50) MAPTSMN1; SMN2LMNANPC1RECQL
SCHEMBL24306925 1.00 MAPT (0.50) MAPTSMN1; SMN2LMNANPC1RECQL
SCHEMBL24403775 1.00 MAPT (0.50) MAPTSMN1; SMN2LMNANPC1RECQL
SCHEMBL24307048 1.00 MAPT (0.50) MAPTSMN1; SMN2LMNANPC1RECQL
SCHEMBL23759549 0.98 HPRT1 (0.50) MAPTSMN1; SMN2LMNANPC1RECQL
SCHEMBL23759550 0.98 HPRT1 (0.50) MAPTSMN1; SMN2LMNANPC1RECQL
SCHEMBL23759344 0.98 HPRT1 (0.50) MAPTSMN1; SMN2LMNANPC1RECQL
SCHEMBL22186526 0.98 MAPT (0.51) MAPTSMN1; SMN2LMNANPC1RECQL
SCHEMBL17691923 0.98 MAPT (0.51) MAPTSMN1; SMN2LMNANPC1RECQL
SCHEMBL24306524 0.96 ALDH1A1 (0.50) MAPTSMN1; SMN2LMNANPC1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024143905-A1 ORGANIC ELECTRIC ELEMENT USING ORGANIC ELECTRIC ELEMENT COMPOUND, AND ELECTRONIC DEVICE 덕산네오룩스 주식회사 2024-07-04 WO disclosed
US-20230139032-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-05-04 US disclosed
US-20230139032-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-05-04 US disclosed
US-20220052271-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-02-17 US disclosed
US-20210359216-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2021-11-18 US disclosed
US-20210305519-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-09-30 US disclosed
US-20210296595-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2021-09-23 US disclosed
US-20200212310-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230139032-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME NECTIN4, L1CAM, EPHA6 MAPT 1927/4885SMN1; SMN2 2240/4885LMNA 4539/4885
US-20200212310-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME SOD1, TRPA1, LPO MAPT 380/4885SMN1; SMN2 718/4885LMNA 1004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.