SCHEMBL22186247

SCHEMBL22186247

C#CCNC(=O)OCOC(=O)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.33
BTN3A1 O00481 3/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26577692 0.80
SCHEMBL26577188 0.79 ALDH1A1 (0.34) ALDH1A1
SCHEMBL26958452 0.77
SCHEMBL18816748 0.76 ACHE (0.36) PRKCABTN3A1ALDH1A1
SCHEMBL681950 0.76 PRKCA (0.46) PRKCABTN3A1ALDH1A1
SCHEMBL29172779 0.76 KMT2A (0.41)
SCHEMBL11923118 0.75 CYP2D6 (0.41) PRKCABTN3A1ALDH1A1
SCHEMBL1892987 0.75 PRKCA (0.33) PRKCABTN3A1ALDH1A1
SCHEMBL22186293 0.75 L3MBTL1 (0.40) ALDH1A1
SCHEMBL1883074 0.75 ACHE (0.35) PRKCABTN3A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3674289-B9 LONG-ACTING RASAGILINE PRODRUG, PREPARATION METHOD AND USE THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO LTD (CN) 2023-12-13 EP disclosed
EP-3674289-B1 LONG-ACTING RASAGILINE PRODRUG, PREPARATION METHOD AND USE THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO LTD (CN) 2023-10-11 EP disclosed
EP-3674289-A1 LONG-ACTING RASAGILINE PRODRUG, PREPARATION METHOD AND USE THEREOF Guangzhou Henovcom Bioscience Co., Ltd (CN) 2020-07-01 EP disclosed