Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trinitrophenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 11/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | TTR | P02766 | 1/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.76 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.76 |
| ▸ | RECQL | P46063 | 1/20 | 0.76 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.76 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trinitrophenol SCHEMBL253750 | 0.98 | GPR35 (0.79) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL8744 | 0.98 | GPR35 (0.79) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL1692116 | 0.95 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL18691159 | 0.95 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL7133013 | 0.95 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL1503376 | 0.95 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL2197458 | 0.95 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL9140811 | 0.95 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL2260890 | 0.95 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL11746249 | 0.95 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260110607-A1 | TRANSPORT AND DETECTION OF EXPLOSIVE SAMPLES WITH MINIMIZED FALSE POSITIVES | ALTI LLC (US) | 2026-04-23 | — | — | US | claimed |
| US-12517047-B2 | Transport and detection of explosive samples | ALTI LLC (US) | 2026-01-06 | — | — | US | claimed |
| US-20250237601-A1 | TRANSPORT AND DETECTION OF EXPLOSIVE SAMPLES | ALTI LLC | 2025-07-24 | — | — | US | claimed |
| CN-219572843-U | Safety detonator without initiating explosive | 上海鲲程电子科技有限公司 | 2023-08-22 | — | — | CN | claimed |
| WO-2022153314-A1 | A PROCESS FOR BLASTING | TAMAR ISRAELI ADVANCED QUARRYING CO. LTD (IL) | 2022-07-21 | — | — | WO | claimed |
| CN-114560747-A | Fuse small-sized energy-gathering output detonator adopting single charge | 南京理工大学 | 2022-05-31 | — | — | CN | claimed |
| US-20190106364-A1 | GAS PROPELLED MUNITIONS ANTI-FOULING SYSTEM | ADLER CAPITAL LLC (US) | 2019-04-11 | — | — | US | claimed |
| CN-108327441-A | A kind of preparation method of stereoscopic crystal glue flower picture | 广州市景与艺文化传播有限公司 | 2018-07-27 | — | — | CN | claimed |
| WO-2017172712-A2 | GAS PROPELLED MUNITIONS ANTI-FOULING SYSTEM | ADLER CAPITAL LLC (US) | 2017-10-05 | — | — | WO | claimed |
| CN-105378216-A | Encapsulated explosive for drilling wellbores | HALLIBURTON ENERGY SERVICES INC | 2016-03-02 | — | — | CN | claimed |
| CN-101439263-B | Device and method for liquid sheet transmission of lead ion using calix [4] arenederivatives liquid sheet carrier | UNIV DONGHUA | 2011-02-09 | — | — | CN | claimed |
| CN-101439263-A | Device and method for liquid sheet transmission of lead ion using calix [4] arenederivatives liquid sheet carrier | UNIV DONGHUA (CN) | 2009-05-27 | — | — | CN | claimed |
| EP-1854160-A2 | REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2007-11-14 | — | — | EP | claimed |
| WO-2006085319-A2 | REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME | YEDA RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2006-08-17 | — | — | WO | claimed |
| US-20050188874-A1 | Use of a microjet reactor for the production of initiating explosive | DELPHI TECHNOLOGIES, INC. | 2005-09-01 | — | — | US | claimed |
| US-6651563-B2 | Filament component of a primer, heat-conducting additive, oxidant, and a binder, and a power component that produces hot reaction particles, an oxidant, and a binder | DYNAMIT NOBEL ARTIENGESELLSCHAFT (DE) | 2003-11-25 | — | — | US | claimed |
| US-20030005989-A1 | Filament component of a primer, heat-conducting additive, oxidant, and a binder, and a power component that produces hot reaction particles, an oxidant, and a binder | AUTOLIV DEVELOPMENT AB (SE) | 2003-01-09 | — | — | US | claimed |
| EP-0781260-B1 | IGNITION ELEMENTS AND FINELY ADJUSTABLE IGNITION COMPOSITIONS | DYNAMIT NOBEL AG (DE) | 2001-12-12 | — | — | EP | claimed |
| US-20010030007-A1 | Ignition elements and finely graduatable ignition components | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 2001-10-18 | — | — | US | claimed |
| US-4455150-A | Chemically enhanced combustion of water-slurry fuels | OLEN KENNETH R | 1984-06-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260110607-A1 | TRANSPORT AND DETECTION OF EXPLOSIVE SAMPLES WITH MINIMIZED FALSE POSITIVES | TES, TNPO1, SLC2A1 | GPR35 1862/4885ALDH1A1 4406/4885HPGD 658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.