SCHEMBL22186502

SCHEMBL22186502

c1ccc(-c2cccc(-n3c4ccc5c6ccccc6n(-c6ccccc6)c5c4c4ccc5ccccc5c43)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
ATM Q13315 2/20 0.41
KDM4E B2RXH2 1/20 0.41
KMT2A Q03164 3/20 0.33
IL1R1 P14778 1/20 0.33
MEN1 O00255 2/20 0.33
GAA P10253 1/20 0.33
ALDH1A1 P00352 3/20 0.33
HTT P42858 2/20 0.33
MAPT P10636 1/20 0.33
RXFP1 Q9HBX9 1/20 0.32
PDE10A Q9Y233 1/20 0.32
FAAH O00519 1/20 0.32
HSP90AA1 P07900 1/20 0.32
PKM P14618 1/20 0.32
MGLL Q99685 1/20 0.32
WNK1 Q9H4A3 1/20 0.32
EGFR P00533 1/20 0.31
ERBB2 P04626 1/20 0.31
CYP1A1 P04798 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21369386 1.00 L3MBTL1 (0.41) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL17990425 0.99 L3MBTL1 (0.40) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL22186492 0.98 L3MBTL1 (0.39) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL22186489 0.98 L3MBTL1 (0.39) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL23960921 0.92 L3MBTL1 (0.38) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL22186225 0.91 L3MBTL1 (0.41) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL22186503 0.91 L3MBTL1 (0.44) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL22186485 0.91 L3MBTL1 (0.44) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL26154836 0.91 L3MBTL1 (0.44) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL25098441 0.91 KDM4E (0.47) L3MBTL1ATMKDM4EKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200212310-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212310-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME SOD1, TRPA1, LPO L3MBTL1 23/4885ATM 3092/4885KDM4E 3013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.