SCHEMBL22187293

SCHEMBL22187293

CCOc1ccc(S(=O)(=O)Oc2ccc(NC(=O)Nc3ccc(OS(=O)(=O)c4ccc(OCC)cc4)cc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.64
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA9 Q16790 1/20 0.58
MEN1 O00255 6/20 0.57
KMT2A Q03164 6/20 0.57
LMNA P02545 4/20 0.56
TDP1 Q9NUW8 2/20 0.56
POLB P06746 2/20 0.56
CYP1A2 P05177 1/20 0.56
ALDH1A1 P00352 6/20 0.56
MAPK1 P28482 2/20 0.56
RAB9A P51151 3/20 0.55
GAA P10253 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
NPC1 O15118 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
PKM P14618 1/20 0.54
RECQL P46063 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22187254 0.90 NPC1 (0.60) MAPTCA12CA1CA2CA9
SCHEMBL29673589 0.90 NPC1 (0.60) MAPTCA12CA1CA2CA9
SCHEMBL22187342 0.89 CA12 (0.66) MAPTCA12CA1CA2CA9
SCHEMBL22187399 0.89 CA12 (0.74) MAPTCA12CA1CA2CA9
SCHEMBL29673526 0.89 ALDH1A1 (0.73) MAPTMEN1KMT2ALMNATDP1
SCHEMBL29673724 0.88 CA12 (0.67) MAPTCA12CA1CA2CA9
SCHEMBL22187484 0.88 CA12 (0.67) MAPTCA12CA1CA2CA9
SCHEMBL11518673 0.88 MEN1 (0.63) MAPTCA1CA2MEN1KMT2A
SCHEMBL22187348 0.86 ENPP1 (0.58) MAPTCA12CA1CA2CA9
SCHEMBL22187433 0.85 MAPK1 (0.59) MAPTCA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method RICOH COMPANY, LTD. (JP) 2026-05-12 US disclosed
EP-4253075-B1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SANKO CO LTD (JP) 2025-10-15 EP disclosed
US-20240190816-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SANKO CO., LTD. (JP) 2024-06-13 US disclosed
US-20240181797-A1 THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2024-06-06 US disclosed
US-11945769-B2 N,N′-diarylurea derivative, manufacturing method thereof, and thermosensitive recording material using same SANKO CO., LTD. (JP) 2024-04-02 US disclosed
EP-4313612-A1 THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD Ricoh Company, Ltd. (JP) 2024-02-07 EP disclosed
CN-117083182-A Thermosensitive recording layer forming liquid, thermosensitive recording medium, production method thereof, and image recording method 株式会社理光 2023-11-17 CN disclosed
EP-4253075-A2 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME Sanko Co., Ltd. (JP) 2023-10-04 EP disclosed
EP-3677569-A9 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME Sanko Co., Ltd. (JP) 2023-08-23 EP disclosed
WO-2022202154-A1 THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2022-09-29 WO disclosed
CN-111032626-B N, N' -diaryl urea derivative, process for producing the same, and thermosensitive recording material using the same 三光株式会社 2022-05-17 CN disclosed
US-20210340099-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SANKO CO., LTD. (JP) 2021-11-04 US disclosed
EP-3677569-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME Sanko Co., Ltd. (JP) 2020-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11945769-B2 N,N′-diarylurea derivative, manufacturing method thereof, and thermosensitive recording material using same SCN1A, SCN1B, NAAA MAPT 3553/4885CA12 1731/4885CA1 398/4885
US-20210340099-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SCN1A, SCN1B, NAAA MAPT 3555/4885CA12 1665/4885CA1 394/4885
US-20240190816-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SCN1A, SCN1B, SCN2A MAPT 3377/4885CA12 1565/4885CA1 343/4885
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method TRPA1, ASIC1, LRBA MAPT 1312/4885CA12 161/4885CA1 139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.