SCHEMBL22190023

SCHEMBL22190023

N[C@H](Cc1cccc(-c2ccccc2)c1)C(=O)O

nearest known ligand 0.79

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GRIA2 P42262 1/20 0.79
SLC7A5 Q01650 5/20 0.70
ALPI P09923 1/20 0.70
PKM P14618 1/20 0.70
PTGS1 P23219 1/20 0.70
XIAP P98170 1/20 0.70
MAPK1 P28482 1/20 0.63
NOS3 P29474 2/20 0.59
NOS1 P29475 2/20 0.59
NOS2 P35228 2/20 0.59
TPH1 P17752 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1904776 1.00 GRIA2 (0.79) GRIA2SLC7A5ALPIPKMPTGS1
SCHEMBL31398345 1.00 GRIA2 (0.79) GRIA2SLC7A5ALPIPKMPTGS1
SCHEMBL16465139 1.00 GRIA2 (0.79) GRIA2SLC7A5ALPIPKMPTGS1
Hydrochloric Acid SCHEMBL7568949 0.98 GRIA2 (0.77) GRIA2SLC7A5ALPIPKMPTGS1
Hydrochloric Acid SCHEMBL7568954 0.98 GRIA2 (0.77) GRIA2SLC7A5ALPIPKMPTGS1
SCHEMBL944210 0.96 GRIA2 (0.84) GRIA2SLC7A5ALPIPKMPTGS1
SCHEMBL29217053 0.96 GRIA2 (0.84) GRIA2SLC7A5ALPIPKMPTGS1
SCHEMBL31688962 0.89 GRIA2 (0.69) GRIA2SLC7A5ALPIPKMPTGS1
SCHEMBL31369787 0.89 GRIA2 (0.69) GRIA2SLC7A5ALPIPKMPTGS1
SCHEMBL31369588 0.89 GRIA2 (0.69) GRIA2SLC7A5ALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250361273-A1 METHODS AND COMPOSITIONS FLAGSHIP PIONEERING INNOVATIONS VII, LLC 2025-11-27 US disclosed
US-12077611-B2 Cyclic peptides multimers targeting α4β7 integrin ZEALAND PHARMA A/S (DK) 2024-09-03 US disclosed
US-20230406884-A1 CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN ZEALAND PHARMA A/S (DK) 2023-12-21 US disclosed
US-11713338-B2 Cyclic peptides multimers targeting α-4-β-7 integrin ZEALAND PHARMA A/S (DK) 2023-08-01 US disclosed
US-20220324909-A1 THERAPEUTIC PEPTIDES COHBAR, INC. 2022-10-13 US disclosed
US-11111273-B2 Cyclic peptides multimers targeting alpha-4-beta-7 integrin ZEALAND PHARMA A/S (DK) 2021-09-07 US disclosed
US-20200216501-A1 CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN ZEALAND PHARMA A/S (DK) 2020-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11111273-B2 Cyclic peptides multimers targeting alpha-4-beta-7 integrin ITGB7, ITGB4, ITGA4 GRIA2 2746/4885SLC7A5 2407/4885ALPI 3773/4885
US-12077611-B2 Cyclic peptides multimers targeting α4β7 integrin ITGB7, ITGB4, ITGA4 GRIA2 2770/4885SLC7A5 2076/4885ALPI 3864/4885
US-20250361273-A1 METHODS AND COMPOSITIONS MC4R, GPR119, MC2R GRIA2 897/4885SLC7A5 2654/4885ALPI 776/4885
US-20200216501-A1 CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN ITGB7, ITGB4, ITGA4 GRIA2 2746/4885SLC7A5 2407/4885ALPI 3773/4885
US-20230406884-A1 CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN ITGB7, ITGB4, ITGA4 GRIA2 2746/4885SLC7A5 2407/4885ALPI 3773/4885
US-11713338-B2 Cyclic peptides multimers targeting α-4-β-7 integrin ITGB7, ITGB4, ITGA4 GRIA2 2820/4885SLC7A5 2493/4885ALPI 3753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.