Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.42 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2219131 | 1.00 | SRD5A1 (0.47) | SRD5A1SRD5A2ALDH1A1NPC1RAB9A | |
| SCHEMBL15672967 | 0.93 | SRD5A1 (0.52) | SRD5A1SRD5A2ALDH1A1NPC1RAB9A | |
| SCHEMBL13539591 | 0.90 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AL3MBTL1POLB | |
| SCHEMBL15693736 | 0.90 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AL3MBTL1POLB | |
| SCHEMBL2216749 | 0.89 | HSD11B1 (0.51) | ALDH1A1NPC1RAB9AL3MBTL1HTT | |
| SCHEMBL2217633 | 0.89 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9AL3MBTL1POLB | |
| SCHEMBL2219414 | 0.89 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9AL3MBTL1POLB | |
| SCHEMBL2216745 | 0.89 | HSD11B1 (0.51) | ALDH1A1NPC1RAB9AL3MBTL1HTT | |
| SCHEMBL2217629 | 0.89 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9AL3MBTL1POLB | |
| SCHEMBL2220385 | 0.88 | HTT (0.52) | ALDH1A1NPC1RAB9AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785452-B2 | Anti-infective compounds | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2014-07-22 | — | — | US | disclosed |
| EP-2730576-A2 | Anti-infective compounds | Institut Pasteur Korea (KR) | 2014-05-14 | — | — | EP | disclosed |
| US-20110178077-A1 | Anti-infective compounds | INSTITUT PASTEUR KOREA (KR) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178077-A1 | Anti-infective compounds | RABGGTB, ELANE, SERPINB1 | SRD5A1 3994/4885SRD5A2 4097/4885ALDH1A1 3932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.