Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEL | Q05823 | 6/20 | 0.59 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.59 |
| ▸ | TGM2 | P21980 | 1/20 | 0.58 |
| ▸ | NT5E | P21589 | 1/20 | 0.58 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.55 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.54 |
| ▸ | KRAS | P01116 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22193779 | 0.95 | RNASEL (0.67) | RNASEL | |
| SCHEMBL2315645 | 0.87 | NT5E (0.69) | RNASELTAS1R3TAS1R1TGM2NT5E | |
| SCHEMBL31310507 | 0.86 | TAS1R3 (0.67) | RNASELTAS1R3TAS1R1TGM2NT5E | |
| SCHEMBL23635808 | 0.85 | RNASEL (0.79) | RNASEL | |
| SCHEMBL18320601 | 0.84 | NT5E (0.72) | RNASELTAS1R3TAS1R1TGM2NT5E | |
| SCHEMBL23430070 | 0.84 | RNASEL (0.82) | RNASEL | |
| SCHEMBL21140197 | 0.84 | RNASEL (0.82) | RNASEL | |
| SCHEMBL23430015 | 0.84 | RNASEL (0.82) | RNASEL | |
| SCHEMBL23430014 | 0.84 | RNASEL (0.82) | RNASEL | |
| SCHEMBL23752167 | 0.84 | TGM2 (0.70) | RNASELTAS1R3TAS1R1TGM2NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021141862-A1 | METHODS OF MODULATING STING PATHWAY ACTIVATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-07-15 | — | — | WO | disclosed |
| EP-2992000-B1 | CYCLIC DI-NUCLEOTIDE INDUCTION OF TYPE I INTERFERON | UNIV CALIFORNIA (US) | 2020-07-08 | — | — | EP | disclosed |