SCHEMBL22197320

SCHEMBL22197320

OCc1ccc(Oc2ccc(C3(c4ccccc4)c4cc(Br)ccc4-c4ccc(Br)cc43)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.50
TTR P02766 1/20 0.38
PDK2 Q15119 4/20 0.36
SRD5A2 P31213 1/20 0.35
NR1H2 P55055 2/20 0.34
NR1H3 Q13133 2/20 0.34
FYN P06241 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33
FFAR1 O14842 1/20 0.33
TSHR P16473 1/20 0.33
NR3C1 P04150 1/20 0.32
RHEB Q15382 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14823249 0.86 PDK2 (0.42) LTA4HPDK2NR1H2MAOAMAOB
SCHEMBL6441263 0.86 PDK2 (0.42) LTA4HPDK2NR1H2MAOAMAOB
SCHEMBL12545282 0.84 PDE4D (0.43) MAOAMAOBTSHR
SCHEMBL13129740 0.82 PDK2 (0.43) LTA4HPDK2MAOAMAOBSMN1; SMN2
SCHEMBL22197292 0.80 ALDH1A1 (0.40) TTRPDK2MAOAMAOBSMN1; SMN2
SCHEMBL21793205 0.80 LTA4H (0.46) LTA4HPDK2NR1H2MAOAMAOB
SCHEMBL3852074 0.79 ALDH1A1 (0.39) PDK2MAOAMAOBSMN1; SMN2OPRM1
SCHEMBL13129739 0.79 PDK2 (0.37) LTA4HPDK2MAOAMAOBSMN1; SMN2
SCHEMBL29540116 0.78 PDK2 (0.47) PDK2SMN1; SMN2OPRM1OPRD1
SCHEMBL1307887 0.78 PDK2 (0.47) PDK2SMN1; SMN2OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11472901-B2 Polymer, coating composition comprising same, and organic light-emitting device using same LG CHEM, LTD. 2022-10-18 US disclosed
US-11374175-B2 Polymer, coating composition comprising same, and organic light-emitting device using same LG CHEM, LTD. 2022-06-28 US disclosed
US-20200239610-A1 Polymer, Coating Composition Comprising Same, and Organic Light-Emitting Device Using Same LG CHEM, LTD. (KR) 2020-07-30 US disclosed
US-20200235301-A1 Polymer, Coating Composition Comprising Same, and Organic Light-Emitting Device Using Same LG CHEM, LTD. (KR) 2020-07-23 US disclosed
EP-3677602-A1 POLYMER, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT-EMITTING DEVICE USING SAME LG CHEM, LTD. (KR) 2020-07-08 EP disclosed
EP-3677606-A1 POLYMER, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT-EMITTING DEVICE USING SAME LG CHEM, LTD. (KR) 2020-07-08 EP disclosed