SCHEMBL29374176

SCHEMBL29374176

Nc1ccc(-c2cc(=O)c3cc(O)ccc3o2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LCK P06239 3/20 1.00
▸ MAPT P10636 5/20 0.82
▸ NPC1 O15118 4/20 0.82
▸ RAB9A P51151 4/20 0.82
▸ SMN1; SMN2 Q16637 4/20 0.82
▸ CYP3A4 P08684 4/20 0.82
▸ HPGD P15428 4/20 0.82
▸ TP53 P04637 3/20 0.82
▸ IP6K2 Q9UHH9 2/20 0.82
▸ LMNA P02545 1/20 0.82
▸ THRB P10828 1/20 0.82
▸ ALOX15 P16050 1/20 0.82
▸ CASP3 P42574 1/20 0.82
▸ SENP8 Q96LD8 1/20 0.82
▸ SENP7 Q9BQF6 1/20 0.82
▸ SENP6 Q9GZR1 1/20 0.82
▸ EGFR P00533 2/20 0.77
▸ SRC P12931 1/20 0.77
▸ CSNK2A2 P19784 5/20 0.74
▸ CSNK2B P67870 5/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3644507 1.00 LCK (1.00) LCKMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL31741263 0.91 MAPT (1.00) LCKMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL311405 0.91 MAPT (1.00) LCKMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL31238426 0.85 MAPT (0.94) LCKMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL10305788 0.85 CSNK2A2 (1.00) LCKMAPTNPC1RAB9ASMN1; SMN2
6-Hydroxyflavone SCHEMBL676594 0.84 MAPT (1.00) LCKMAPTNPC1RAB9ASMN1; SMN2
6-Hydroxyflavone SCHEMBL29628861 0.84 MAPT (1.00) LCKMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL31238388 0.82 MAPT (0.78) LCKMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL311326 0.82 MAPT (0.78) LCKMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL29664594 0.82 ALOX5 (0.78) LCKMAPTNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12548678-B2 Methods and systems for machine learning analysis of single nucleotide polymorphisms in lupus AMPEL BIOSOLUTIONS, LLC (US) 2026-02-10 — — US claimed
US-20260128175-A1 Methods and Systems for Analysis of Gene Expression Data AMPEL BIOSOLUTIONS LLC (US) 2026-05-07 — — US disclosed
US-12594345-B2 Degradable hyaluronic acid hydrogels ASCENDIS PHARMA A/S (DK) 2026-04-07 — — US disclosed
US-12548678-B2 Methods and systems for machine learning analysis of single nucleotide polymorphisms in lupus AMPEL BIOSOLUTIONS, LLC (US) 2026-02-10 — — US disclosed
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 — — EP disclosed
US-20250078957-A1 Unsupervised Machine Learning Methods AMPEL BIOSOLUTIONS LLC (US) 2025-03-06 — — US disclosed
US-20250022541-A1 Unsupervised Machine Learning Methods AMPEL BIOSOLUTIONS LLC (US) 2025-01-16 — — US disclosed
US-20250011886-A1 Systems and Methods for Targeting COVID-19 Therapies AMPEL BIOSOLUTIONS, LLC 2025-01-09 — — US disclosed
US-20240428948-A1 Unsupervised Machine Learning Methods AMPEL BIOSOLUTIONS LLC (US) 2024-12-26 — — US disclosed
EP-4479973-A1 UNSUPERVISED MACHINE LEARNING METHODS Ampel Biosolutions, LLC (US) 2024-12-25 — — EP disclosed
EP-3230319-B1 ANTI-PD-1 ANTIBODIES AND METHODS OF USE THEREOF RINAT NEUROSCIENCE CORP (US) 2022-09-07 — — EP disclosed
US-20220273585-A1 Composition comprising at least one natural or synthetic non-euphoric cannabinoid and its method of manufacture TILMAN (BE) 2022-09-01 — — US disclosed
EP-4049654-A1 COMPOSITION COMPRISING AT LEAST ONE NATURAL OR SYNTHETIC CANNABINOID WITHOUT EUPHORIC EFFECT AND MANUFACTURING METHOD THEREOF Eleonor (BE) 2022-08-31 — — EP disclosed
US-20220249657-A1 ANTI-PD-1 ANTIBODIES AND METHODS OF USE THEREOF RINAT NEUROSCIENCE CORP. (US) 2022-08-11 — — US disclosed
EP-4011396-A1 RELEASABLE CONJUGATES QuiaPEG Pharmaceuticals AB (SE) 2022-06-15 — — EP disclosed
US-11338035-B2 Anti-PD-1 antibodies and methods of use thereof RINAT NEUROSCIENCE CORP. (US) 2022-05-24 — — US disclosed
EP-3989943-A1 COMPOSITION COMPRISING AT LEAST ONE TRITERPENE AND/OR AT LEAST ONE TRITERPENOID AND/OR AT LEAST ONE OF THE GLYCOSYLATED FORMS THEREOF Tilman (BE) 2022-05-04 — — EP disclosed
WO-2022079090-A1 COMPOSITION COMPRISING AT LEAST ONE LABDANE DITERPENE AND METHOD FOR MANUFACTURING SAME TILMAN SA (BE) 2022-04-21 — — WO disclosed
US-20220081412-A1 QUINOLINYL-PYRAZINE-CARBOXAMIDE COMPOUNDS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2022-03-17 — — US disclosed
US-20220040145-A1 INHIBITORS OF MICROBIALLY INDUCED AMYLOID AXIAL THERAPEUTICS, INC. 2022-02-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273585-A1 Composition comprising at least one natural or synthetic non-euphoric cannabinoid and its method of manufacture CNR2, CNR1, FAAH LCK 2651/4885MAPT 584/4885NPC1 219/4885
US-20220081412-A1 QUINOLINYL-PYRAZINE-CARBOXAMIDE COMPOUNDS AND USES THEREOF HMGB3, HCCS, ACACA LCK 2749/4885MAPT 4430/4885NPC1 107/4885
US-12594345-B2 Degradable hyaluronic acid hydrogels CD44, H1-0, MMP1 LCK 4514/4885MAPT 4452/4885NPC1 3038/4885
US-20220040145-A1 INHIBITORS OF MICROBIALLY INDUCED AMYLOID APP, PSEN1, BACE1 LCK 3041/4885MAPT 9/4885NPC1 905/4885
US-20260128175-A1 Methods and Systems for Analysis of Gene Expression Data IRAK4, TLR4, TLR2 LCK 447/4885MAPT 3797/4885NPC1 3587/4885
US-12548678-B2 Methods and systems for machine learning analysis of single nucleotide polymorphisms in lupus SSB, METTL16, TLR9 LCK 3368/4885MAPT 4802/4885NPC1 2071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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