Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.52 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAD51 | Q06609 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL2220070 | 0.99 | P2RY2 (0.51) | P2RY12P2RY2CARM1PRMT1CA1 | |
| SCHEMBL2206062 | 0.98 | P2RY12 (0.54) | P2RY12P2RY2CARM1PRMT1CA1 | |
| SCHEMBL2219284 | 0.92 | P2RY2 (0.48) | P2RY12P2RY2CARM1PRMT1CA1 | |
| SCHEMBL2218463 | 0.92 | P2RY2 (0.54) | P2RY12P2RY2CARM1PRMT1CA1 | |
| SCHEMBL2217201 | 0.91 | P2RY2 (0.47) | P2RY12P2RY2CARM1PRMT1CA1 | |
| SCHEMBL2219341 | 0.91 | P2RY2 (0.47) | P2RY12P2RY2CARM1PRMT1CA1 | |
| SCHEMBL2204401 | 0.88 | MAPT (0.46) | P2RY12P2RY2CARM1PRMT1CA1 | |
| SCHEMBL2206639 | 0.87 | MAPT (0.48) | P2RY12P2RY2CARM1PRMT1CA1 | |
| Potassium SCHEMBL2219777 | 0.87 | MAPT (0.45) | P2RY12P2RY2CARM1PRMT1CA1 | |
| SCHEMBL2206071 | 0.87 | CA1 (0.45) | P2RY12P2RY2CARM1PRMT1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2722190-A1 | Optimized undercoat for thermal recording material | Ricoh Industrie France SAS (FR) | 2014-04-23 | — | — | EP | disclosed |
| US-8546300-B2 | Thermosensitive recording material and image recording method | RICOH COMPANY, LTD. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-20110177941-A1 | THERMOSENSITIVE RECORDING MATERIAL AND IMAGE RECORDING METHOD | RICOH COMPANY, LTD. (JP) | 2011-07-21 | — | — | US | disclosed |