Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 4/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688869 | 0.95 | PPARD (0.44) | GPR3FFAR4SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL28452075 | 0.85 | SLC6A4 (0.45) | SLC6A4HTR2AKCNH2ARACHE | |
| SCHEMBL22199039 | 0.85 | GPR3 (0.46) | GPR3FFAR4SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1148826 | 0.83 | SLC6A4 (0.44) | FFAR4SLC6A4SLC6A2SLC6A3MCHR1 | |
| SCHEMBL446449 | 0.83 | AR (0.47) | SLC6A4HTR2AKCNH2ARACHE | |
| SCHEMBL12259242 | 0.81 | AR (0.47) | SLC6A4HTR2AKCNH2AR | |
| SCHEMBL10801181 | 0.81 | GPR3 (0.43) | GPR3FFAR4ACHE | |
| SCHEMBL22184955 | 0.81 | ALDH1A1 (0.46) | FFAR4SLC6A4SLC6A2SLC6A3MCHR1 | |
| SCHEMBL19175092 | 0.80 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL24512646 | 0.80 | TTR (0.46) | FFAR4SLC6A4SLC6A2SLC6A3SCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141439-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-09 | — | — | WO | disclosed |