Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1242525 | 0.87 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3L3MBTL1RAB9A | |
| SCHEMBL2749090 | 0.86 | MAPT (0.45) | L3MBTL1ALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL2992329 | 0.86 | ALDH1A1 (0.52) | SLC6A4RAB9AALDH1A1SMN1; SMN2TEAD4 | |
| SCHEMBL3003478 | 0.84 | ALDH1A1 (0.55) | RAB9AALDH1A1SMN1; SMN2TEAD4MAPT | |
| SCHEMBL29688467 | 0.84 | ALDH1A1 (0.55) | RAB9AALDH1A1SMN1; SMN2TEAD4MAPT | |
| SCHEMBL1155719 | 0.84 | ALDH1A1 (0.55) | RAB9AALDH1A1SMN1; SMN2TEAD4MAPT | |
| SCHEMBL31457276 | 0.84 | ALDH1A1 (0.55) | RAB9AALDH1A1SMN1; SMN2TEAD4MAPT | |
| SCHEMBL10627888 | 0.84 | FFAR4 (0.42) | SLC6A4FFAR4FFAR1PPARD | |
| SCHEMBL22199038 | 0.83 | GPR3 (0.47) | SLC6A4SLC6A2SLC6A3MCHR1FFAR4 | |
| SCHEMBL9204260 | 0.83 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1SMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040041-A1 | QUINOLINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | Dongguan HEC Pesticides R&D Co., Ltd. (CN) | 2021-02-11 | — | — | US | disclosed |
| EP-1780202-B1 | QUINOLINE DERIVATIVE AND INSECTICIDE CONTAINING SAME AS ACTIVE CONSTITUENT | MEIJI SEIKA PHARMA CO LTD (JP) | 2013-02-27 | — | — | EP | disclosed |
| US-7880006-B2 | 4-Acetoxy-5-chloro-6-(4-chlorophenoxy)-2,3-dimethyl-quinoline, used as agricultural and horticultural insecticides | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-02-01 | — | — | US | disclosed |
| US-20070203181-A1 | Quinoline Derivatives And Insecticide Comprising Thereof As Active Ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-08-30 | — | — | US | disclosed |
| EP-1780202-A1 | QUINOLINE DERIVATIVE AND INSECTICIDE CONTAINING SAME AS ACTIVE CONSTITUENT | MEIJI SEIKA KAISHA LTD. (JP) | 2007-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040041-A1 | QUINOLINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | NQO2, RDX, RIN1 | SLC6A4 2488/4885SLC6A2 1227/4885SLC6A3 1510/4885 |
| US-20070203181-A1 | Quinoline Derivatives And Insecticide Comprising Thereof As Active Ingredient | DDT, ACHE, NQO1 | SLC6A4 1492/4885SLC6A2 695/4885SLC6A3 905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.