Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.45 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30892335 | 0.91 | GLA (0.45) | KIF11AKR1C3AKR1C2NPC1MAPT | |
| SCHEMBL278277 | 0.91 | GLA (0.45) | KIF11AKR1C3AKR1C2NPC1MAPT | |
| SCHEMBL15746963 | 0.91 | KIF11 (0.53) | KIF11AKR1C3AKR1C2S100A4NPC1 | |
| SCHEMBL15745809 | 0.85 | TRPV1 (0.39) | KIF11AKR1C3AKR1C2NPC1MAPT | |
| SCHEMBL28424524 | 0.81 | ADH5 (0.48) | KIF11AKR1C3AKR1C2AKR1B10AKR1C4 | |
| SCHEMBL15247155 | 0.80 | GLA (0.36) | KIF11AKR1C3AKR1C2MAPTRAB9A | |
| SCHEMBL17133900 | 0.79 | AKR1C3 (0.60) | KIF11AKR1C3AKR1C2S100A4MAPT | |
| SCHEMBL2154079 | 0.78 | HSP90AA1 (0.41) | S100A4POLBTSHR | |
| SCHEMBL2680326 | 0.78 | NOTUM (0.42) | KIF11NPC1MAPTRAB9AMEN1 | |
| SCHEMBL31542017 | 0.78 | NOTUM (0.42) | KIF11NPC1MAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141713-A1 | METHOD FOR PREPARING POLYAMIC ACID COMPOSITION CONTAINING NOVEL DICARBONYL COMPOUND, POLYAMIC ACID COMPOSITION, METHOD FOR MANUFACTURING POLYAMIDE-IMIDE FILM USING SAME, AND POLYAMIDE-IMIDE FILM PRODUCED BY SAME MANUFACTURING METHOD | 주식회사 대림코퍼레이션 | 2020-07-09 | — | — | WO | disclosed |