Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sebacic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.60 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL78409 | 0.96 | GPR84 (0.67) | GPR84FFAR1FFAR4CAMK2AHDAC3 | |
| Sebacic Acid SCHEMBL28904447 | 0.96 | GPR84 (0.67) | GPR84FFAR1FFAR4CAMK2AHDAC3 | |
| Terephthalic Acid SCHEMBL27915155 | 0.96 | GPR84 (0.67) | GPR84FFAR1FFAR4CAMK2AHDAC3 | |
| Sebacic Acid SCHEMBL28058541 | 0.96 | GPR84 (0.67) | GPR84FFAR1FFAR4CAMK2AHDAC3 | |
| Sebacic Acid SCHEMBL6854591 | 0.94 | GPR84 (0.56) | GPR84FFAR1FFAR4CAMK2AHDAC3 | |
| Azelaic Acid SCHEMBL739682 | 0.94 | GPR84 (0.56) | GPR84FFAR1FFAR4CAMK2AHDAC3 | |
| Sebacic Acid SCHEMBL29140956 | 0.94 | GPR84 (0.56) | GPR84FFAR1FFAR4CAMK2AHDAC3 | |
| Terephthalic Acid SCHEMBL6703188 | 0.94 | GPR84 (0.62) | GPR84FFAR1FFAR4CAMK2AHDAC3 | |
| Terephthalic Acid SCHEMBL27987241 | 0.94 | GPR84 (0.62) | GPR84FFAR1FFAR4CAMK2AHDAC3 | |
| Terephthalic Acid SCHEMBL2420617 | 0.91 | TSHR (0.55) | GPR84FFAR1FFAR4CAMK2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8415021-B2 | Biodegradable starch-containing composition with improved tear strength | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-04-09 | — | — | US | disclosed |
| US-8409677-B2 | Biodegradable starch-containing blend | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-04-02 | — | — | US | disclosed |
| WO-2011090964-A1 | BIODEGRADABLE STARCH-CONTAINING COMPOSITION WITH IMPROVED TEAR STRENGTH | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011091130-A1 | BIODEGRADABLE STARCH-CONTAINING BLEND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-28 | — | — | WO | disclosed |
| US-20110177269-A1 | BIODEGRADABLE STARCH-CONTAINING COMPOSITION WITH IMPROVED TEAR STRENGTH | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-21 | — | — | US | disclosed |
| US-20110177275-A1 | BIODEGRADABLE STARCH-CONTAINING BLEND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-21 | — | — | US | disclosed |