Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sebacic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL29140956 | 1.00 | GPR84 (0.56) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Azelaic Acid SCHEMBL739682 | 1.00 | GPR84 (0.56) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Terephthalic Acid SCHEMBL2420617 | 0.98 | TSHR (0.55) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Azelaic Acid SCHEMBL15377525 | 0.96 | GPR84 (0.52) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Terephthalic Acid SCHEMBL27915155 | 0.94 | GPR84 (0.67) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Sebacic Acid SCHEMBL28058541 | 0.94 | GPR84 (0.67) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Sebacic Acid SCHEMBL28904447 | 0.94 | GPR84 (0.67) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Sebacic Acid SCHEMBL78409 | 0.94 | GPR84 (0.67) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Sebacic Acid SCHEMBL2220001 | 0.94 | GPR84 (0.60) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Azelaic Acid SCHEMBL351913 | 0.93 | LMNA (0.60) | GPR84FFAR1FFAR4HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384364-A | Biodegradable polyester elastomer toughening particles, polyglycolic acid composition and preparation method | 中船鹏力(南京)塑造科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| US-6780940-B2 | MATERIAL WHICH GENERATES HEAT WHEN SUBJECTED TO HIGH FREQUENCY INDUCTION AND A THERMOPLASTIC RESIN MODIFIED WITH A MONOMER HAVING A FUNCTIONAL GROUP WHICH REACTS WITH AN INORGANIC | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2004-08-24 | — | — | US | disclosed |
| US-20020061968-A1 | Adhesive resin composition and method for separating adherends bonded together by the compostion | TOYO BOSEKI KABUSHIKI KAISHA | 2002-05-23 | — | — | US | disclosed |
| EP-1191079-A2 | Adhesive resin compositions and method for separating adherends bonded together by the composition | Toyo Boseki Kabushiki Kaisha (JP) | 2002-03-27 | — | — | EP | disclosed |