Sebacic Acid

Sebacic Acid

SCHEMBL78409

O=C(O)CCCCCCCCC(=O)O.O=C(O)c1ccc(C(=O)O)cc1.OCCCCO

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Sebacic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.67
FFAR1 O14842 1/20 0.67
FFAR4 Q5NUL3 1/20 0.67
CAMK2A Q9UQM7 1/20 0.52
HDAC3 O15379 1/20 0.52
HDAC4 P56524 1/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC7 Q8WUI4 1/20 0.52
HDAC2 Q92769 1/20 0.52
HDAC10 Q969S8 1/20 0.52
HDAC11 Q96DB2 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
HDAC9 Q9UKV0 1/20 0.52
HDAC5 Q9UQL6 1/20 0.52
MAPK1 P28482 1/20 0.52
TSHR P16473 2/20 0.50
LMNA P02545 2/20 0.50
NFKB1 P19838 1/20 0.50
PMP22 Q01453 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sebacic Acid SCHEMBL28058541 1.00 GPR84 (0.67) GPR84FFAR1FFAR4CAMK2AHDAC3
Sebacic Acid SCHEMBL28904447 1.00 GPR84 (0.67) GPR84FFAR1FFAR4CAMK2AHDAC3
Terephthalic Acid SCHEMBL27915155 1.00 GPR84 (0.67) GPR84FFAR1FFAR4CAMK2AHDAC3
Terephthalic Acid SCHEMBL6703188 0.98 GPR84 (0.62) GPR84FFAR1FFAR4CAMK2AHDAC3
Terephthalic Acid SCHEMBL27987241 0.98 GPR84 (0.62) GPR84FFAR1FFAR4CAMK2AHDAC3
Sebacic Acid SCHEMBL2220001 0.96 GPR84 (0.60) GPR84FFAR1FFAR4CAMK2AHDAC3
Sebacic Acid SCHEMBL6854591 0.94 GPR84 (0.56) GPR84FFAR1FFAR4CAMK2AHDAC3
Azelaic Acid SCHEMBL739682 0.94 GPR84 (0.56) GPR84FFAR1FFAR4CAMK2AHDAC3
Sebacic Acid SCHEMBL29140956 0.94 GPR84 (0.56) GPR84FFAR1FFAR4CAMK2AHDAC3
Benzoic Acid SCHEMBL15352622 0.92 HDAC3 (0.63) GPR84FFAR1FFAR4CAMK2AHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230028583-A1 PROTECTIVE POLYAMIDE FILM FOR TAPE MEASURES DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2023-01-26 US claimed
CN-109906114-A Spherical particle 巴斯夫欧洲公司 2019-06-18 CN claimed
US-8936852-B2 Breathable, heat-sealable composite polymeric film DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2015-01-20 US claimed
US-20130299374-A1 Breathable, heat-sealable composite polymeric film DUPONT TEIJIN FILMS US LTD (US) 2013-11-14 US claimed
JP-4773676-B2 2011-09-14 JP claimed
US-7368165-B2 Process for the production of coated polymeric film DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2008-05-06 US claimed
EP-1362075-B1 PROCESS FOR THE PRODUCTION OF COATED POLYMERIC FILM DUPONT TEIJIN FILMS US LTD (US) 2007-10-03 EP claimed
US-20050249906-A1 Heat-sealable coating of a copolyester of an aromatic dicarboxylc acid, an aliphatic dicarboxylic acid, and an aliphatic or cycloaliphatic glycol that is less than 8 mu m thick; lids for convenience food and beverage containers SANKEY STEPHEN W 2005-11-10 US claimed
US-6939584-B2 Process for the production of coated polymeric film DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP 2005-09-06 US claimed
JP-2004518007-A 2004-06-17 JP claimed
US-20040067284-A1 Heat-sealable polymeric film comprising a substrate layer (especially polyethylene terephthalate) having a coating of a heat-sealable copolyester; food packaging such as a lid for a container DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP 2004-04-08 US claimed
EP-1362075-A1 PROCESS FOR THE PRODUCTION OF COATED POLYMERIC FILM Dupont Teijin Films U.S. Limited Partnership (US) 2003-11-19 EP claimed
WO-2002059186-A1 PROCESS FOR THE PRODUCTION OF COATED POLYMERIC FILM DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2002-08-01 WO claimed
US-20240002118-A1 FIBROUS CONTAINERS FOR OVENABLE PRODUCTS DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2024-01-04 US disclosed
EP-4217194-A1 FIBROUS CONTAINERS FOR OVENABLE PRODUCTS Dupont Teijin Films U.S. Limited Partnership (US) 2023-08-02 EP disclosed
US-20230110933-A1 POLYMERIC FILM TUBE DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2023-04-13 US disclosed
WO-2003015768-A2 USE OF INHIBITORS OF PROLINE ENDOPEPTIDASE TO MODULATE INOSITOL (1,4,5) TRIPHOSPHATE CONCENTRATION DEPENDENT ON INTRACELLULAR SIGNAL CASCADES PROBIODRUG AG (DE) 2003-02-27 WO disclosed
WO-2002059186-A1 PROCESS FOR THE PRODUCTION OF COATED POLYMERIC FILM DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2002-08-01 WO disclosed
WO-2002026493-A1 MULTI-LAYER POLYMERIC FILM DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2002-04-04 WO disclosed
US-4309518-A ADDING POLYETHER ESTER AMIDE TO INCREASE NOTCH IMPACT STRENGTH CHEMISCHE WERKE HUELS, AKTIENGESELLSCHAFT (DE) 1982-01-05 US disclosed