Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Azelaic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL29140956 | 1.00 | GPR84 (0.56) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Sebacic Acid SCHEMBL6854591 | 1.00 | GPR84 (0.56) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Terephthalic Acid SCHEMBL2420617 | 0.98 | TSHR (0.55) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Azelaic Acid SCHEMBL15377525 | 0.96 | GPR84 (0.52) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Terephthalic Acid SCHEMBL27915155 | 0.94 | GPR84 (0.67) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Sebacic Acid SCHEMBL28058541 | 0.94 | GPR84 (0.67) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Sebacic Acid SCHEMBL28904447 | 0.94 | GPR84 (0.67) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Sebacic Acid SCHEMBL78409 | 0.94 | GPR84 (0.67) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Sebacic Acid SCHEMBL2220001 | 0.94 | GPR84 (0.60) | GPR84FFAR1FFAR4HDAC3HDAC4 | |
| Azelaic Acid SCHEMBL351913 | 0.93 | LMNA (0.60) | GPR84FFAR1FFAR4HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114845865-A | Protective polyamide film for tape measure | 美国杜邦泰津胶片合伙人有限公司 | 2022-08-02 | — | — | CN | claimed |
| EP-2431177-B1 | Polyester film | DUPONT TEIJIN FILMS U S LTD PARTNERSHIP (US) | 2017-04-26 | — | — | EP | claimed |
| US-8936852-B2 | Breathable, heat-sealable composite polymeric film | DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) | 2015-01-20 | — | — | US | claimed |
| US-20130299374-A1 | Breathable, heat-sealable composite polymeric film | DUPONT TEIJIN FILMS US LTD (US) | 2013-11-14 | — | — | US | claimed |
| EP-2077943-B1 | HEAT-SEALABLE COMPOSITE POLYESTER FILM | DUPONT TEIJIN FILMS US LTD (US) | 2013-02-13 | — | — | EP | claimed |
| EP-1984177-B1 | POLYESTER FILM | DUPONT TEIJIN FILMS US LTD (US) | 2012-07-11 | — | — | EP | claimed |
| US-8202612-B2 | Polyester film | DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) | 2012-06-19 | — | — | US | claimed |
| EP-2431177-A1 | Polyester film | DuPont Teijin Films U.S. Limited Partnership (US) | 2012-03-21 | — | — | EP | claimed |
| US-20100068355-A1 | HEAT-SEALABLE COMPOSITE POLYESTER FILM | DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) | 2010-03-18 | — | — | US | claimed |
| US-20100003377-A1 | POLYESTER FILM | DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) | 2010-01-07 | — | — | US | claimed |
| EP-2077943-A1 | HEAT-SEALABLE COMPOSITE POLYESTER FILM | Dupont Teijin Films U.S. Limited Partnership (US) | 2009-07-15 | — | — | EP | claimed |
| EP-1984177-A1 | POLYESTER FILM | Dupont Teijin Films U.S. Limited Partnership (US) | 2008-10-29 | — | — | EP | claimed |
| WO-2008053205-A1 | HEAT-SEALABLE COMPOSITE POLYESTER FILM | DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) | 2008-05-08 | — | — | WO | claimed |
| US-7368165-B2 | Process for the production of coated polymeric film | DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) | 2008-05-06 | — | — | US | claimed |
| WO-2007093798-A1 | POLYESTER FILM | DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) | 2007-08-23 | — | — | WO | claimed |
| US-20050249906-A1 | Heat-sealable coating of a copolyester of an aromatic dicarboxylc acid, an aliphatic dicarboxylic acid, and an aliphatic or cycloaliphatic glycol that is less than 8 mu m thick; lids for convenience food and beverage containers | SANKEY STEPHEN W | 2005-11-10 | — | — | US | claimed |
| US-6939584-B2 | Process for the production of coated polymeric film | DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP | 2005-09-06 | — | — | US | claimed |
| US-20240002118-A1 | FIBROUS CONTAINERS FOR OVENABLE PRODUCTS | DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) | 2024-01-04 | — | — | US | disclosed |
| CN-1822993-A | Breathable polymeric films | DUPONT TEIJIN FILMS US LTD (US) | 2006-08-23 | — | — | CN | disclosed |
| CN-1558827-A | Multi-layer polymeric film for packaging ovenable meals | 美国杜邦泰津胶片合伙人有限公司 | 2004-12-29 | — | — | CN | disclosed |