SCHEMBL22201171

SCHEMBL22201171

NC(=O)CC12CC3CC(C1)C1(CCC1)C(C3)C2

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BPTF Q12830 1/20 0.40
ALDH1A1 P00352 5/20 0.40
TSHR P16473 2/20 0.40
LMNA P02545 1/20 0.37
NPSR1 Q6W5P4 1/20 0.35
HSD11B1 P28845 2/20 0.34
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
P2RX7 Q99572 1/20 0.33
CCR2 P41597 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1478949 0.80 ALDH1A1 (0.57) BPTFALDH1A1TSHRLMNANPSR1
SCHEMBL22201129 0.76 BPTF (0.35) BPTFALDH1A1TSHRLMNANPSR1
SCHEMBL25879662 0.75
Adamantaneacetic Acid SCHEMBL6531436 0.73 POLB (0.58) BPTFALDH1A1TSHRLMNANPSR1
SCHEMBL24201886 0.72 ALDH1A1 (0.48) BPTFALDH1A1TSHRLMNANPSR1
SCHEMBL1160738 0.70 ALDH1A1 (0.43) BPTFALDH1A1TSHRLMNANPSR1
SCHEMBL16684407 0.69 ALDH1A1 (0.44) BPTFALDH1A1TSHRLMNANPSR1
SCHEMBL7412340 0.69 ALDH1A1 (0.39) BPTFALDH1A1TSHRLMNANPSR1
SCHEMBL4541131 0.68 ALDH1A1 (0.36) BPTFALDH1A1TSHRLMNAKDM4E
SCHEMBL5327206 0.68 ALDH1A1 (0.41) BPTFALDH1A1TSHRLMNAHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020141734-A1 METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR 기초과학연구원 2020-07-09 WO disclosed