Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 11/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | FLT1 | P17948 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201251 | 0.87 | MKNK1 (0.47) | ABCG2TGFBR1EGFRFLT1KDR | |
| SCHEMBL22201263 | 0.85 | TGFBR1 (0.61) | PRKD1ABCG2TGFBR1EGFRFLT1 | |
| SCHEMBL22201373 | 0.84 | ABCG2 (0.45) | ABCG2 | |
| SCHEMBL22201397 | 0.83 | ABCG2 (0.55) | PRKD1ABCG2FGFR2FLT3 | |
| SCHEMBL22201407 | 0.73 | TGFBR1 (0.60) | PRKD1ABCG2TGFBR1KDM1A | |
| SCHEMBL22201274 | 0.73 | TGFBR1 (0.63) | ABCG2TGFBR1EGFRFLT1CSNK2A1 | |
| SCHEMBL22201393 | 0.70 | ABCG2 (0.55) | ABCG2TGFBR1 | |
| SCHEMBL3041415 | 0.70 | TGFBR1 (0.47) | ABCG2TGFBR1EGFRFLT1KDM1A | |
| SCHEMBL22803770 | 0.69 | EGFR (0.58) | PRKD1TGFBR1FGFR2FLT3EGFR | |
| SCHEMBL30302532 | 0.69 | EGFR (0.58) | PRKD1TGFBR1FGFR2FLT3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |