Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCH | P24723 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 10/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201226 | 0.91 | PRKCH (0.37) | PRKCHPRKCESYKKCNH2AURKB | |
| SCHEMBL22201366 | 0.91 | MAPT (0.39) | SYKKDM4EMEN1KMT2AHPGD | |
| SCHEMBL22201368 | 0.88 | SYK (0.45) | SYKMEN1KMT2ATGFBR1ALDH1A1 | |
| SCHEMBL22201323 | 0.88 | SYK (0.38) | PRKCHPRKCESYKKDM4EMEN1 | |
| SCHEMBL22201417 | 0.87 | P2RX3 (0.38) | PRKCHPRKCESYKAURKBTGFBR1 | |
| SCHEMBL22201421 | 0.87 | SYK (0.36) | PRKCHPRKCESYKKCNH2AURKB | |
| SCHEMBL22201537 | 0.86 | KDM4E (0.42) | ROCK2KDM4EMEN1KMT2AHPGD | |
| SCHEMBL22201489 | 0.86 | SYK (0.37) | PRKCHPRKCESYKKDM4EMEN1 | |
| SCHEMBL22201286 | 0.86 | P2RX3 (0.40) | SYKMAPTAURKBTGFBR1ALDH1A1 | |
| SCHEMBL22201488 | 0.86 | ADORA3 (0.37) | PRKCHPRKCESYKKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |