Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 6/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201400 | 0.88 | KMT2A (0.37) | SYKALOX12ALDH1A1ROCK2MEN1 | |
| SCHEMBL22201302 | 0.88 | SYK (0.44) | SYKALOX12ALDH1A1ROCK2MEN1 | |
| SCHEMBL22201293 | 0.88 | SYK (0.44) | SYKALOX12ALDH1A1ROCK2MEN1 | |
| SCHEMBL22201305 | 0.88 | SYK (0.44) | SYKALOX12ALDH1A1ROCK2MEN1 | |
| SCHEMBL22201292 | 0.87 | SYK (0.42) | SYKLMNASMN1; SMN2UBE2MDCUN1D1 | |
| SCHEMBL22201267 | 0.86 | ABL1 (0.38) | SYKLMNASMN1; SMN2P2RX3NPC1 | |
| SCHEMBL22201245 | 0.85 | SYK (0.42) | SYKALOX12ALDH1A1ROCK2MEN1 | |
| SCHEMBL22201368 | 0.84 | SYK (0.45) | SYKALOX12ALDH1A1MEN1KMT2A | |
| SCHEMBL22201306 | 0.84 | SYK (0.41) | SYKALOX12ALDH1A1ROCK2KMT2A | |
| SCHEMBL22201519 | 0.83 | SYK (0.40) | SYKALOX12ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |