Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201564 | 0.88 | RIPK1 (0.36) | SYKRIPK1P2RX3RIPK2RIPK3 | |
| SCHEMBL22201526 | 0.88 | ABL1 (0.35) | SYKRIPK1P2RX3RIPK2RIPK3 | |
| SCHEMBL22201376 | 0.86 | SYK (0.39) | SYKP2RX3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22201304 | 0.83 | SYK (0.43) | SYKP2RX3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22201305 | 0.83 | SYK (0.44) | SYKP2RX3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22201302 | 0.83 | SYK (0.44) | SYKP2RX3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22201293 | 0.83 | SYK (0.44) | SYKP2RX3ALDH1A1ALOX12KMT2A | |
| SCHEMBL22201245 | 0.83 | SYK (0.42) | SYKP2RX3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22201292 | 0.83 | SYK (0.42) | SYKLMNASMN1; SMN2GAA | |
| SCHEMBL22201368 | 0.80 | SYK (0.45) | SYKP2RX3ALDH1A1ALOX12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |