Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 12/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | LATS2 | Q9NRM7 | 6/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201550 | 0.89 | POLB (0.58) | LATS1POLBKDM4EALDH1A1LMNA | |
| SCHEMBL22201418 | 0.81 | ABCG2 (0.47) | LATS1POLBKDM4EPRKCQPRKCD | |
| SCHEMBL22201395 | 0.78 | FGFR2 (0.55) | LATS1POLBKDM4EALDH1A1LMNA | |
| SCHEMBL22201545 | 0.74 | KDM4E (0.72) | LATS1POLBKDM4EALDH1A1LMNA | |
| SCHEMBL22201427 | 0.69 | LATS1 (0.47) | LATS1POLBKDM4EALDH1A1LMNA | |
| SCHEMBL22201294 | 0.69 | LATS1 (0.48) | LATS1POLBKDM4EALDH1A1LMNA | |
| SCHEMBL22201396 | 0.69 | TGFBR1 (0.53) | LATS1POLBKDM4EALDH1A1LMNA | |
| SCHEMBL22201348 | 0.69 | PRKD1 (0.60) | LATS1POLBKDM4EALDH1A1LMNA | |
| SCHEMBL14344390 | 0.68 | TGFBR1 (0.78) | LATS1POLBKDM4EALDH1A1LMNA | |
| SCHEMBL1146190 | 0.68 | PRKCQ (0.61) | PRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |