Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 14/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LATS1 | O95835 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201550 | 0.85 | POLB (0.58) | ABCG2POLBLATS1KDM4E | |
| SCHEMBL22201308 | 0.81 | LATS1 (0.49) | POLBLATS1KDM4EPRKCQPRKCD | |
| SCHEMBL22201397 | 0.79 | ABCG2 (0.55) | ABCG2 | |
| SCHEMBL22201408 | 0.72 | ABCG2 (0.53) | ABCG2POLB | |
| SCHEMBL22201259 | 0.71 | ABCG2 (0.51) | ABCG2 | |
| SCHEMBL22201545 | 0.70 | KDM4E (0.72) | ABCG2POLBLATS1KDM4E | |
| SCHEMBL22201393 | 0.70 | ABCG2 (0.55) | ABCG2 | |
| SCHEMBL1146188 | 0.70 | PRKCQ (0.54) | PRKCQPRKCD | |
| SCHEMBL4840411 | 0.70 | ABCG2 (0.86) | ABCG2POLBKDM4E | |
| SCHEMBL22201285 | 0.68 | ABCG2 (0.55) | ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |