Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 12/20 | 0.55 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.49 |
| ▸ | STK3 | Q13188 | 2/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.49 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | BLK | P51451 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201265 | 0.88 | PRKD1 (0.53) | ROCK2TGFBR1ABCG2GRM5GRM1 | |
| SCHEMBL22201445 | 0.80 | ROCK2 (0.51) | ROCK2TGFBR1ROCK1CSNK2A1STK3 | |
| SCHEMBL5005160 | 0.79 | CDK9 (0.49) | — | |
| SCHEMBL31471912 | 0.79 | CDK7 (0.57) | AURKBCDK2PAK1 | |
| SCHEMBL31110487 | 0.77 | NAMPT (0.50) | GRM5GRM1NAMPT | |
| SCHEMBL9952896 | 0.77 | NAMPT (0.50) | GRM5GRM1NAMPT | |
| SCHEMBL5661370 | 0.76 | CDK9 (0.56) | — | |
| SCHEMBL5001788 | 0.75 | CDK9 (0.48) | ROCK2ROCK1GRM5GRM1NAMPT | |
| SCHEMBL14520516 | 0.75 | CDK9 (0.48) | ROCK2ROCK1NAMPT | |
| SCHEMBL1728902 | 0.75 | ROCK2 (0.64) | ROCK2ROCK1CSNK2A1STK3AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |