Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 1/20 | 0.53 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 6/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201444 | 0.88 | ROCK2 (0.55) | TGFBR1ABCG2GRM5GRM1NAMPT | |
| SCHEMBL5001675 | 0.79 | CCNT1 (0.49) | JAK1CNR1GABRPGABRDGABRA1 | |
| SCHEMBL31471912 | 0.78 | CDK7 (0.57) | JAK1 | |
| SCHEMBL5001670 | 0.77 | HTR6 (0.44) | TGFBR1JAK1GRM5GRM1NAMPT | |
| SCHEMBL19838779 | 0.76 | JAK1 (0.52) | TGFBR1JAK1GRM5GRM1NAMPT | |
| SCHEMBL14520510 | 0.74 | CDK9 (0.48) | JAK1NAMPTCNR1GABRPGABRD | |
| SCHEMBL14500619 | 0.74 | CDK9 (0.48) | JAK1GRM5GRM1NAMPTCNR1 | |
| SCHEMBL22467649 | 0.73 | JAK1 (0.50) | JAK1GRM5GRM1NAMPTPDE10A | |
| SCHEMBL30593499 | 0.73 | JAK1 (0.50) | JAK1GRM5GRM1NAMPTPDE10A | |
| SCHEMBL5522323 | 0.73 | PRKCQ (0.58) | JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |