Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.56 |
| ▸ | PRKCH | P24723 | 1/20 | 0.54 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.53 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201369 | 0.82 | LMNA (0.63) | ABCG2PRKCHPRKCEALDH1A1POLB | |
| SCHEMBL22201624 | 0.81 | ABCG2 (0.83) | ABCG2ABCB1TGFBR1L3MBTL1MEN1 | |
| SCHEMBL22201452 | 0.78 | PRKCH (0.58) | ABCG2PRKCHPRKCEABCB1TGFBR1 | |
| SCHEMBL4903516 | 0.75 | MAPK8 (0.68) | PRKCHPRKCEGSK3B | |
| SCHEMBL22201381 | 0.74 | PRKCH (0.51) | ABCG2PRKCHPRKCETGFBR1MEN1 | |
| SCHEMBL22201642 | 0.74 | PRKCH (0.53) | ABCG2PRKCHPRKCEABCB1TGFBR1 | |
| SCHEMBL22201379 | 0.73 | NPC1 (0.50) | PRKCHPRKCEL3MBTL1MEN1KMT2A | |
| SCHEMBL22201469 | 0.73 | FGFR2 (0.62) | PRKCHPRKCETGFBR1HPGDLMNA | |
| SCHEMBL22201641 | 0.73 | RIPK2 (0.55) | PRKCHPRKCETGFBR1 | |
| SCHEMBL29817992 | 0.72 | ROCK1 (0.52) | ABCG2MEN1KMT2AGSK3BROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |