Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | GSK3A | P49840 | 1/20 | 0.63 |
| ▸ | GSK3B | P49841 | 1/20 | 0.63 |
| ▸ | PRKCH | P24723 | 1/20 | 0.57 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 11/20 | 0.54 |
| ▸ | SYK | P43405 | 3/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201452 | 0.84 | PRKCH (0.58) | LMNAHPGDALDH1A1POLBGSK3A | |
| SCHEMBL22201282 | 0.84 | HPGD (0.64) | LMNAHPGDALDH1A1POLBGSK3A | |
| SCHEMBL22201448 | 0.82 | ABCG2 (0.56) | LMNAHPGDALDH1A1POLBGSK3A | |
| SCHEMBL22201642 | 0.79 | PRKCH (0.53) | LMNAHPGDALDH1A1POLBGSK3A | |
| SCHEMBL22201469 | 0.78 | FGFR2 (0.62) | LMNAHPGDPRKCHPRKCESYK | |
| SCHEMBL22201641 | 0.78 | RIPK2 (0.55) | PRKCHPRKCESYKEGFR | |
| SCHEMBL22201398 | 0.78 | ABCG2 (0.84) | LMNAHPGDALDH1A1POLBGSK3A | |
| SCHEMBL1083761 | 0.78 | HPGD (1.00) | LMNAHPGDALDH1A1POLBGSK3A | |
| SCHEMBL22201449 | 0.78 | PRKCH (0.51) | LMNAHPGDALDH1A1POLBGSK3A | |
| SCHEMBL22201450 | 0.78 | PRKCH (0.51) | LMNAHPGDPRKCHPRKCESYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |