Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 14/20 | 0.55 |
| ▸ | PRKCH | P24723 | 1/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | RIPK3 | Q9Y572 | 4/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201452 | 0.84 | PRKCH (0.58) | PRKCHPRKCETGFBR1SYK | |
| SCHEMBL22201674 | 0.81 | HPGD (0.64) | TGFBR1PRKD1 | |
| SCHEMBL22201635 | 0.81 | PRKD1 (0.46) | RIPK2PRKCHPRKCETGFBR1EGFR | |
| SCHEMBL22201638 | 0.79 | KMT2A (0.57) | PRKCHPRKCETGFBR1KDRPRKD1 | |
| SCHEMBL22201369 | 0.78 | LMNA (0.63) | PRKCHPRKCEEGFRSYK | |
| SCHEMBL22201449 | 0.77 | PRKCH (0.51) | PRKCHPRKCESYK | |
| SCHEMBL22201384 | 0.77 | PRKCH (0.51) | PRKCHPRKCE | |
| SCHEMBL22201642 | 0.77 | PRKCH (0.53) | PRKCHPRKCETGFBR1EGFRSYK | |
| SCHEMBL22201470 | 0.76 | PRKCH (0.47) | PRKCHPRKCETGFBR1PRKD1SYK | |
| SCHEMBL22201469 | 0.76 | FGFR2 (0.62) | PRKCHPRKCETGFBR1EGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |